Safety and factors related to survival after percutaneous endoscopic gastrostomy in ALS

被引:101
|
作者
Chiò, A [1 ]
Finocchiaro, E
Meineri, P
Bottacchi, E
Schiffer, D
机构
[1] Univ Turin, Dept Neurosci, I-10126 Turin, Italy
[2] San Giovanni Hosp, Dept Clin Nutr, Turin, Italy
[3] Gen Reg Hosp, Dept Neurol, Aosta, Italy
[4] Univ Turin, Dept Gastroenterol, I-10126 Turin, Italy
[5] Santa Croce Hosp, Dept Neurol, Cuneo, Italy
关键词
percutaneous endoscopic gastrostomy; amyotrophic lateral sclerosis;
D O I
10.1212/WNL.53.5.1123
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Percutaneous endoscopic gastrostomy (PEG) has been proposed as symptomatic treatment of dysphagia in patients with ALS. Safety and factors related to survival after PEG were analyzed in 50 consecutive ALS patients. No major acute or long-term complications were observed. Stabilization or increase in weight were observed after PEG. Median survival after PEG was 185 days, with a worse outcome in patients with weight loss greater than or equal to 10% healthy body weight and forced vital capacity <65%. PEG may be a useful option in the symptomatic treatment of dysphagia in ALS.
引用
收藏
页码:1123 / 1125
页数:3
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