Total synthesis of natural (+)-membrenone C and its 7-epimer

被引：41
|
作者：
Yadav, JS [1 ]
Srinivas, R [1 ]
Sathaiah, K [1 ]
机构：
[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 2006年 / 47卷 / 10期
关键词：
(+)-membrenone C and its 7-epimer; desymmetrization technique;
D O I：
10.1016/j.tetlet.2005.12.129
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Highly stereoselective asymmetric total syntheses of the polypropionate marine defense substance (+)-membrenone C and its 7-epimer have been achieved. Highlights of the strategy include the utilization of a desymmetrization technique to create five contiguous chiral centres from a single bicyclic precursor. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1603 / 1606
页数：4
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