Studies on nitrogen-containing heterocyclic compounds. Novel synthesis of naphtho[1,2-b and 2,1-b][1,8]naphthyridines and oxidation reactions with peroxy acids

被引：7

作者：

Takeuchi, I

Asai, K

Hamada, Y

Masuda, H

Suezawa, H

Hirota, M

Kurono, Y

Hatano, K

机构：

[1] YOKOHAMA NATL UNIV,FAC ENGN,DEPT SYNTHET CHEM,HODOGAYA KU,YOKOHAMA,KANAGAWA 240,JAPAN

[2] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

来源：

HETEROCYCLES | 1996年 / 43卷 / 10期

关键词：

D O I：

10.3987/COM-96-7525

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A modified Friedlander condensation of 2-aminonicotinaldehyde with alpha- and beta-naphthols lead successfully to two new naphtho[1,2-b and 2,1-b][1,8]-naphthyridines in a single synthetic procedure. The oxidation of the naphthonaphthyridines with peroxy acids afforded novel products such as a seven-membered oxazepine moiety. Structures were characterized by standard spectroscopy. The crystal and molecular structures (3) and (4) were determined by X-ray analyses.

引用

页码：2139 / 2152

页数：14

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