The Role of Hyaluronidase in the Treatment of Complications From Hyaluronic Acid Dermal Fillers

被引：126

作者：

Cavallini, Maurizio

Gazzola, Riccardo ^{[1
]}

Metalla, Marco

Vaienti, Luca ^{[1
]}

机构：

[1] IRCCS Policlin San Donato, Dept Plast Surg, Milan, Italy

来源：

AESTHETIC SURGERY JOURNAL | 2013年 / 33卷 / 08期

关键词：

noninvasive plastic surgery; fillers; facial skin necrosis; cosmetic medicine; hyaluronidase; hyaluronic acid; dermal; MEDIATED ALLERGIC REACTION; PERIBULBAR ANESTHESIA; ORBITAL INFLAMMATION; INJECTION; CELLULITIS; MANAGEMENT;

D O I：

10.1177/1090820X13511970

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Knowledge of the use, methods of application, and adverse effects of hyaluronidases is essential for the aesthetic practitioner. Therefore, we performed an extensive review of the available literature from 1928 to 2011 and compared the different enzymes available, recording each author's indications regarding usage and side effects.

引用

页码：1167 / 1174

页数：8

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