Preoperative Embolization of Cerebral Arteriovenous Malformations with Onyx

被引:38
|
作者
Hauck, E. F. [1 ]
Welch, B. G. [1 ,2 ]
White, J. A. [1 ]
Purdy, P. D. [2 ]
Pride, L. G. [2 ]
Samson, D. [1 ]
机构
[1] Univ Texas SW Med Ctr Dallas, Dept Neurosurg, Dallas, TX 75390 USA
[2] Univ Texas SW Med Ctr Dallas, Dept Neuroradiol, Dallas, TX 75390 USA
关键词
ENDOVASCULAR TREATMENT; BRAIN; COMPLICATIONS;
D O I
10.3174/ajnr.A1376
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND AND PURPOSE: Preoperative embolization facilitates the surgical management of complex cerebral arteriovenous malformations (cAVMs). This analysis aims to investigate the risks for preoperative cAVM embolization with Onyx. MATERIALS AND METHODS: We retrospectively analyzed clinical data of all patients who underwent embolization with Onyx as a preoperative treatment of cAVMs at our institution since 2005 (US Food and Drug Administration [FDA] approval). Patients with arteriovenous fistulas were excluded. A total of 107 patients were treated for cAVMs during the study period. Of those patients, 41 underwent cAVM embolizations with Onyx in 82 procedures. RESULTS: After the embolization, the cAVM diameter was reduced from 3.71 +/- 1.55 cm to 3.06 +/- 1.89 cm (P <.05). Median volume reduction was 75%. Complete occlusion with embolization alone was achieved in 4 (10%) cAVMs. The recurrence rate for completely occluded cAVMs was 50% (2 patients). A total of 71% of the 41 patients treated with Onyx underwent surgery, and 15% underwent radiosurgery. There were 9% who have not yet received definitive treatment of their residual cAVMs. A new permanent neurologic deficit occurred in 5 patients (6.1% per procedure or 12.2% per patient). CONCLUSIONS: A considerable risk for a permanent neurologic deficit remains for cAVM embolization with Onyx. The risk has to be carefully weighted against the benefit of volume reduction in the treatment of cAVMs.
引用
收藏
页码:492 / 495
页数:4
相关论文
共 50 条
  • [31] Embolization of peripheral high-flow arteriovenous malformations with Onyx
    Kilani, M. Saeed
    Lepennec, V.
    Petit, P.
    Magalon, G.
    Casanova, D.
    Bartoli, J. -M.
    Vidal, V.
    DIAGNOSTIC AND INTERVENTIONAL IMAGING, 2017, 98 (03) : 216 - 225
  • [32] Embolization of Intracranial Arteriovenous Malformations Using Onyx in 53 Patients
    Aoude, Ahmad
    Ghanaati, Hossein
    Jouibari, Morteza Faghih
    Shakiba, Madjid
    Khaleghi, Mehdi
    Nowrouzi, Abbas
    IRANIAN JOURNAL OF RADIOLOGY, 2017, 14 (03)
  • [33] Onyx Embolization of Arteriovenous Malformations Using 2 Microcatheters COMMENTS
    Albuquerque, Felipe C.
    Bendok, Bernard R.
    Nimmagadda, Anitha
    NEUROSURGERY, 2010, 66 (03) : 618 - 619
  • [34] Complications of embolization for cerebral arteriovenous malformations
    Sugiu, K
    Tokunaga, K
    Sasahara, W
    Watanabe, K
    Nishida, A
    Ono, S
    Nishio, S
    Date, I
    Rüfenacht, DA
    INTERVENTIONAL NEURORADIOLOGY, 2004, 10 : 59 - 61
  • [35] Embolization of arteriovenous malformations with onyx:: Clinicopathological experience in 23 patients
    Jahan, R
    Murayama, Y
    Gobin, YP
    Duckwiler, GR
    Vinters, HV
    Viñuela, F
    NEUROSURGERY, 2001, 48 (05) : 984 - 995
  • [36] Preoperative embolization of brain arteriovenous malformations Response
    Donzelli, Grace F.
    Nelson, Jeffrey
    Kim, Helen
    Cooke, Daniel L.
    JOURNAL OF NEUROSURGERY, 2020, 132 (06) : 2015 - 2016
  • [37] Cerebral Abscess After Onyx Embolization of an Arteriovenous Malformation
    Shah, Kevin A.
    Katz, Jeffrey M.
    Dehdashti, Amir R.
    WORLD NEUROSURGERY, 2020, 135 : 96 - 99
  • [38] Cerebral arteriovenous fistula to pulmonary artery onyx embolization
    T E Herman
    M J Siegel
    A Vachharajani
    P Masand
    D Cross
    Journal of Perinatology, 2007, 27 : 238 - 240
  • [39] Cerebral arteriovenous fistula to pulmonary artery onyx embolization
    Herman, T. E.
    Siegel, M. J.
    Vachharajani, A.
    Masand, P.
    Cross, D.
    JOURNAL OF PERINATOLOGY, 2007, 27 (04) : 238 - 240
  • [40] Onyx and arteriovenous malformations
    Elhammady, Mohamed Samy
    Heros, Roberto C.
    JOURNAL OF NEUROSURGERY, 2011, 115 (01) : 75 - 76