Multiple Novel Engineered AAV Capsids Demonstrate Enhanced Brain and Spinal Cord Gene Transfer after Systemic Administration in Adult Mice

被引:0
|
作者
Murlidharan, Giridhar [1 ]
Wang, Hongxing [1 ]
Adachi, Kei [1 ]
Christensen, Emily [1 ]
Thompson, Jeff [1 ]
Felix-Ortiz, Ada [1 ]
Goulet, Martin [1 ]
Tam Nguyen [1 ]
Johnson, Brianna [1 ]
Liu, Li [1 ]
Zhou, Joice [1 ]
Paranjpe, Maneesha [1 ]
Chung, Charlotte [1 ]
Aubin, Justin [1 ]
Sah, Dinah [1 ]
Carter, Todd [1 ]
Hou, Jay [1 ]
机构
[1] Voyager Therapeut, Cambridge, MA USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
240
引用
收藏
页码:119 / 119
页数:1
相关论文
共 50 条
  • [1] Novel AAV Capsids for Enhanced Gene Transfer to the Cerebellum, Spinal Cord, and Schwann Cells
    Chen, Xin
    Dong, Thomas
    Casy, Widler
    Hu, Yuhui
    Chen, Daphne
    McCown, Thomas
    Gray, Steven
    MOLECULAR THERAPY, 2021, 29 (04) : 157 - 157
  • [2] Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS
    Stanton, Alexandra C.
    Lagerborg, Kim A.
    Tellez, Liana
    Krunnfusz, Allison
    King, Emily M.
    Ye, Simon
    Solomon, Isaac H.
    Tabebordbar, Mohammadsharif
    Sabeti, Pardis C.
    MED, 2023, 4 (01): : 31 - +
  • [3] Identification of Novel AAV Capsids for Enhanced CNS Gene Transfer
    Chen, Daphne
    Watkins, Zachary A.
    Padegimas, Linas
    Zaric, Violeta
    Miller, Timothy J.
    Gray, Steven J.
    MOLECULAR THERAPY, 2018, 26 (05) : 187 - 187
  • [4] Systemic Administration of Novel Engineered AAV Capsids Facilitates Enhanced Transgene Expression in the Macaque Central Nervous System
    Stanton, Alexandra C.
    Lagerborg, Kim A.
    Krunnfusz, Allison
    Tellez, Liana
    King, Emily M.
    Ye, Simon
    Tabebordbar, Mohammadsharif
    Sabeti, Pardis C.
    MOLECULAR THERAPY, 2022, 30 (04) : 207 - 208
  • [5] Augmentation of AAV-mediated cardiac gene transfer after systemic administration in adult rats
    O J Müller
    S Schinkel
    J A Kleinschmidt
    H A Katus
    R Bekeredjian
    Gene Therapy, 2008, 15 : 1558 - 1565
  • [6] Augmentation of AAV-mediated cardiac gene transfer after systemic administration in adult rats
    Mueller, Oliver J.
    Schinkel, Stefanie
    Kleinschmidt, Juergen A.
    Katus, Hugo A.
    Bekeredjian, Raffi
    HUMAN GENE THERAPY, 2007, 18 (10) : 1023 - 1024
  • [7] Augmentation of AAV-mediated cardiac gene transfer after systemic administration in adult rats
    Mueller, O. J.
    Schinkel, S.
    Kleinschmidt, J. A.
    Katus, H. A.
    Bekeredjian, R.
    GENE THERAPY, 2008, 15 (23) : 1558 - 1565
  • [8] Novel AAV Capsids Demonstrate Strong Retinal Expression in Non-Human Primates After Intravitreal Administration
    Kevany, Brian
    Suh, Susie
    Lu, Jennings
    Padegimas, Linas
    Palczewski, Krzysztof
    Miller, Timothy
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [9] Novel AAV Capsids Demonstrate Strong Retinal Expression in Non-Human Primates after Intravitreal Administration
    Kevany, Brian M.
    Suh, Susie
    Lu, Jennings
    Padegimas, Linas
    Palczewski, Krzysztof
    Miller, Timothy J.
    MOLECULAR THERAPY, 2019, 27 (04) : 113 - 113
  • [10] Identification of Novel AAV Capsids for Skeletal Muscle Gene Transfer by In Vivo Selection in Humanized Mice
    Gifford, Jennifer C.
    Neto, Ana
    Syriani, Enrique
    Batista, Ana Rita
    Choudhury, Sourav
    Zhang, Yuanfan
    Black, Aaron
    Golebiowski, Diane
    Malhotra, Jyoti
    Schneider, Joel
    Wagner, Kathryn R.
    Sena-Esteves, Miguel
    MOLECULAR THERAPY, 2018, 26 (05) : 165 - 166