Splenic marginal zone lymphoma in a HIV-1 infected patient: evidence favouring a pathogenetic role of HIV-1 itself in the lymphomagenesis

被引：3
|
作者：
Cagliuso, M. [1 ]
Conti, V. [1 ]
Trasarti, S. [2 ]
Lombardi, L. [2 ]
Riminucci, M. [3 ]
Perez, M. [4 ]
Turriziani, O. [3 ]
Falasca, F. [3 ]
Nanni, M. [2 ]
Tafuri, A. [2 ]
Mezzaroma, I. [1 ]
机构：
[1] Univ Roma La Sapienza, Dept Clin Med, I-00185 Rome, Italy
[2] Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy
[3] Univ Roma La Sapienza, Dept Mol Med, I-00185 Rome, Italy
[4] IRCCS, Lab Histopathol, Ist Dermopat Immacolata, Rome, Italy
来源：
INFECTION | 2013年 / 41卷 / 01期
关键词：
HIV-1; SMZLs; Splenomegaly; B-CELL LYMPHOMA; INFECTION; VIRUS; AIDS; DISEASE;
D O I：
10.1007/s15010-012-0344-4
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
A rare case of splenic marginal zone lymphoma (SMZL) in a human immunodeficiency virus (HIV)-1 infected patient is described. As an association between SMZL and viral infections has been reported, the presence of the hepatitis C virus and HIV-1 genomes was evaluated. Only HIV-1 DNA levels were detected in enriched splenic B lymphocytes, suggesting a HIV-1 involvement in lymphomagenesis.
引用
收藏
页码：255 / 258
页数：4
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