NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection

被引：142
|
作者：
Alter, G. [1 ]
Altfeld, M. [1 ]
机构：
[1] Massachusetts Gen Hosp, Partners AIDS Res Ctr, Charlestown, MA 02129 USA
来源：
JOURNAL OF INTERNAL MEDICINE | 2009年 / 265卷 / 01期
关键词：
HIV; innate immunity; Natural killer cells; viral immunity; NATURAL-KILLER-CELLS; CLASS-I MOLECULES; MHC CLASS-I; IMMUNODEFICIENCY VIRUS-INFECTION; DEPENDENT CELLULAR CYTOTOXICITY; HLA-B; DENDRITIC CELLS; INHIBITORY RECEPTORS; SELF-TOLERANCE; BINDING-SITE;
D O I：
10.1111/j.1365-2796.2008.02045.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Increasing evidence supports the notion that the innate immune response, and in particular, natural killer cells play a central role in determining the quality of the host immune response to infection. In this review we highlight recent evidence that suggests that NK cells influence the clinical fate of HIV-infected individuals.
引用
收藏
页码：29 / 42
页数：14
相关论文
共 50 条
  • [1] NK Cells and immune activation in HIV-1 infection
    Goodier, Martin R.
    RETROVIROLOGY, 2010, 7 : 5 - 5
  • [2] NK Cells and immune activation in HIV-1 infection
    Martin R Goodier
    Retrovirology, 7
  • [3] Mixed cryoglobulinemia in HIV-1 infection: The role of HIV-1
    Dimitrakopoulos, AN
    Kordossis, T
    Hatzakis, A
    Moutsopoulos, HM
    ANNALS OF INTERNAL MEDICINE, 1999, 130 (03) : 226 - 230
  • [4] Immunomodulatory effects of the HIV-1 Vpr protein: Role in the control of HIV-1 infection
    Conti, L
    Matarrese, P
    Varano, B
    Gauzzi, MC
    Sato, A
    Malorni, W
    Belardelli, F
    Gessani, S
    6TH EUROPEAN CONFERENCE ON EXPERIMENTAL AIDS RESEARCH, 2001, : 39 - 43
  • [5] The Role of HIV-1 DNA as an Additional Marker of HIV-1 Infection
    Beloukas, Apostolos
    Paraskevis, Dimitrios
    Psichogiou, Mina
    Hatzakis, Angelos
    CURRENT HIV RESEARCH, 2009, 7 (03) : 255 - 265
  • [6] NK Cell Function in HIV-1 Infection
    De Maria, Andrea
    Moretta, Lorenzo
    CURRENT HIV RESEARCH, 2008, 6 (05) : 433 - 440
  • [7] NK cell function in HIV-1 infection
    Alter, Galit
    Altfeld, Marcus
    CURRENT MOLECULAR MEDICINE, 2006, 6 (06) : 621 - 629
  • [8] HIV-1 transmission and acute HIV-1 infection
    Hansasuta, P
    Rowland-Jones, SL
    BRITISH MEDICAL BULLETIN, 2001, 58 : 109 - 127
  • [9] Role of microglia in HIV-1 infection
    Ruojing Bai
    Chengcheng Song
    Shiyun Lv
    Linlin Chang
    Wei Hua
    Wenjia Weng
    Hao Wu
    Lili Dai
    AIDS Research and Therapy, 20
  • [10] Role of microglia in HIV-1 infection
    Bai, Ruojing
    Song, Chengcheng
    Lv, Shiyun
    Chang, Linlin
    Hua, Wei
    Weng, Wenjia
    Wu, Hao
    Dai, Lili
    AIDS RESEARCH AND THERAPY, 2023, 20 (01)
12345