The chemokine receptor CXCR4 is required for outgrowth of micrometastases because it allows tumor cells to adapt to glucose deprivation.

被引:0
|
作者
Roos, Ed [1 ]
Meijer, Joost [1 ]
机构
[1] Netherlands Canc Inst, Amsterdam, Netherlands
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1088
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Strong expression of chemokine receptor CXCR4 by renal cell carcinoma cells correlates with metastasis
    Linhui Wang
    Liang Wang
    Bo Yang
    Qing Yang
    Shouyi Qiao
    Yingming Wang
    Yinghao Sun
    Clinical & Experimental Metastasis, 2009, 26 : 1049 - 1054
  • [32] Effects of L-Selectin Stimulation of the Expression of Chemokine Receptor CXCR4 on NK Cells of Healthy Donors and Tumor Patients
    Yu. V. Perfilyeva
    E. A. Kustova
    N. T. Urazalieva
    S. A. Baisheva
    A. T. Aubakirova
    R. T. Tleulieva
    N. N. Belyaev
    G. K. Zakiryanova
    Bulletin of Experimental Biology and Medicine, 2012, 153 : 86 - 88
  • [33] Effects of L-Selectin Stimulation of the Expression of Chemokine Receptor CXCR4 on NK Cells of Healthy Donors and Tumor Patients
    Perfilyeva, Yu. V.
    Kustova, E. A.
    Urazalieva, N. T.
    Baisheva, S. A.
    Aubakirova, A. T.
    Tleulieva, R. T.
    Belyaev, N. N.
    Zakiryanova, G. K.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 153 (01) : 86 - 88
  • [34] CXCR4 chemokine receptor mediates prostate tumor cell adhesion through α5 and β3 Integrins
    Engl, Tobias
    Relja, Borna
    Marian, Dana
    Blumenberg, Christa
    Mueller, Iris
    Beecken, Wolf-Dietrich
    Jones, Jon
    Ringel, Eva M.
    Bereiter-Hahn, Juergen
    Jonas, Dietger
    Blaheta, Roman A.
    NEOPLASIA, 2006, 8 (04): : 290 - 301
  • [35] Targeting Chemokine Receptor CXCR4 for Treatment of HIV-1 Infection, Tumor Progression, and Metastasis
    Choi, Won-Tak
    Yang, Yilei
    Xu, Yan
    An, Jing
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2014, 14 (13) : 1574 - 1589
  • [36] Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets
    Kaemmerer, Daniel
    Schindler, Robin
    Mussbach, Franziska
    Dahmen, Uta
    Altendorf-Hofmann, Annelore
    Dirsch, Olaf
    Saenger, Joerg
    Schulz, Stefan
    Lupp, Amelie
    BMC CANCER, 2017, 17
  • [37] Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets
    Daniel Kaemmerer
    Robin Schindler
    Franziska Mußbach
    Uta Dahmen
    Annelore Altendorf-Hofmann
    Olaf Dirsch
    Jörg Sänger
    Stefan Schulz
    Amelie Lupp
    BMC Cancer, 17
  • [38] The Chemokine Receptor CXCR4 and the Metalloproteinase MT1-MMP Are Mutually Required during Melanoma Metastasis to Lungs
    Bartolome, Ruben A.
    Ferreiro, Sergio
    Miquilena-Colina, Maria E.
    Martinez-Prats, Lorena
    Soto-Montenegro, Maria L.
    Garcia-Bernal, David
    Vaquero, Juan J.
    Agami, Reuven
    Delgado, Rafael
    Desco, Manuel
    Sanchez-Mateos, Paloma
    Teixido, Joaquin
    AMERICAN JOURNAL OF PATHOLOGY, 2009, 174 (02): : 602 - 612
  • [39] Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells
    Holland, JD
    Kochetkova, M
    Akekawatchai, C
    Dottore, M
    Lopez, A
    McColl, SR
    CANCER RESEARCH, 2006, 66 (08) : 4117 - 4124
  • [40] High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells
    Ni, HT
    Hu, SX
    Sheng, WS
    Olson, JM
    Cheeran, MCJ
    Chan, ASH
    Lokensgard, JR
    Peterson, PK
    DEVELOPMENTAL BRAIN RESEARCH, 2004, 152 (02): : 159 - 169