An immunostimulating water insoluble β-glucan of an edible hybrid mushroom: Isolation and characterization

被引:10
|
作者
Maity, Kousik [1 ]
Samanta, Surajit [1 ]
Bhanja, Sunil K. [1 ]
Maity, Saikat [1 ]
Sen, Ipsita K. [1 ]
Maiti, Swatilekha [2 ]
Behera, Birendra [2 ]
Maiti, Tapas K. [2 ]
Sikdar, Samir R. [3 ]
Islam, Syed S. [1 ]
机构
[1] Vidyasagar Univ, Dept Chem & Chem Technol, Midnapore 721102, W Bengal, India
[2] Indian Inst Technol, Dept Biotechnol, Kharagpur 721302, W Bengal, India
[3] Bose Inst, Div Plant Biol, Kolkata 700054, W Bengal, India
关键词
Somatic hybrid PCH9FB mushroom; Glucan; Structure; NMR studies; Immunostimulation;
D O I
10.1016/j.fitote.2012.10.014
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
An immunostimulating water-insoluble beta-glucan isolated from hot alkaline extract of the fruiting bodies of an edible somatic hybrid mushroom of Pleurotus florida and Calocybe indica var. APK2 showed significant macrophage, splenocyte, and thymocyte activations. On the basis of total hydrolysis, methylation analysis, and NMR experiments (H-1, C-13, DQF-COSY, TOCSY, NOESY, DEPT-135, and HSQC), the repeating unit of the polysaccharide is established. (c) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:15 / 21
页数:7
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