Alzheimer's Disease-Related Lesions

被引：4

作者：

Alafuzoff, Irina ^{[1
,2
,3
]}

机构：

[1] Uppsala Univ, Dept Immunol Genet & Pathol, S-75185 Uppsala, Sweden

[2] Univ Eastern Finland, Inst Clin Med, Dept Neurol, Kuopio, Finland

[3] Univ Uppsala Hosp, Dept Clin Pathol & Cytol, Uppsala, Sweden

来源：

JOURNAL OF ALZHEIMERS DISEASE | 2013年 / 33卷

关键词：

Aging; Alzheimer's disease-related pathology; amyloid-beta; co-morbidity; hyperphosphorylated tau; immunohistochemistry; neuropathology; alpha-synuclein; BRAINNET EUROPE CONSORTIUM; LEWY BODIES; NEUROFIBRILLARY PATHOLOGY; NEUROPATHOLOGIC ASSESSMENT; PARKINSONS-DISEASE; APOLIPOPROTEIN-E; ALPHA-SYNUCLEIN; DIAGNOSIS; DEMENTIA; PLAQUES;

D O I：

10.3233/JAD-2012-129024

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The invitation to contribute to "Alzheimer's Disease: Advances for a New Century" gave me an opportunity to briefly summarize my personal opinions about how the field of neuropathology has evolved. The goal is to briefly exemplify the changes that have influenced the way we conduct our diagnostic work as well as the way we interpret our results. From an era of histological stains, we have moved to visualization of altered proteins in predicted brain regions; we have also realized that in many aged subjects, not one but a plethora of co-pathologies are seen, and finally, we have become aware that the degenerative process is initiated much earlier than we ever suspected.

引用

页码：S173 / S179

页数：7

共 50 条

[41] Age and Alzheimer's Disease-Related Oligodendrocyte Changes in Hippocampal Subregions
DeFlitch, Leah
Gonzalez-Fernandez, Estibaliz
Crawley, Ilan
Kang, Shin H.
FRONTIERS IN CELLULAR NEUROSCIENCE, 2022, 16
[42] Phenome-wide investigation of Alzheimer's disease-related phenotypes
Chen, Hung-Hsin
Petty, Lauren E.
Bush, William S.
Naj, Adam C.
Below, Jennifer E.
GENETIC EPIDEMIOLOGY, 2018, 42 (07) : 692 - 692
[43] Alzheimer's disease-related transcriptional sex differences in myeloid cells
Coales, Isabelle
Tsartsalis, Stergios
Fancy, Nurun
Weinert, Maria
Clode, Daniel
Owen, David
Matthews, Paul M.
JOURNAL OF NEUROINFLAMMATION, 2022, 19 (01)
[44] African ancestry protects against Alzheimer's disease-related neuropathology
D Schlesinger
L T Grinberg
J G Alba
M S Naslavsky
L Licinio
J M Farfel
C K Suemoto
R E de Lucena Ferretti
R E P Leite
M P de Andrade
A C F dos Santos
H Brentani
C A Pasqualucci
R Nitrini
W Jacob-Filho
M Zatz
Molecular Psychiatry, 2013, 18 : 79 - 85
[45] Alzheimer’s Disease-Related Epigenetic Changes: Novel Therapeutic Targets
Alireza Paniri
Mohammad Mahdi Hosseini
Haleh Akhavan-Niaki
Molecular Neurobiology, 2024, 61 (3) : 1282 - 1317
[46] Tau acts as a mediator for Alzheimer's disease-related synaptic deficits
Liao, Dezhi
Miller, Eric C.
Teravskis, Peter J.
EUROPEAN JOURNAL OF NEUROSCIENCE, 2014, 39 (07) : 1202 - 1213
[47] Alzheimer’s disease-related transcriptional sex differences in myeloid cells
Isabelle Coales
Stergios Tsartsalis
Nurun Fancy
Maria Weinert
Daniel Clode
David Owen
Paul M. Matthews
Journal of Neuroinflammation, 19
[48] Alzheimer's Disease-Related Protein Expression in the Retina of Octodon degus
Du, Lucia Y.
Chang, Lily Y-L.
Ardiles, Alvaro O.
Tapia-Rojas, Cheril
Araya, Joaquin
Inestrosa, Nibaldo C.
Palacios, Adrian G.
Acosta, Monica L.
PLOS ONE, 2015, 10 (08):
[49] Human Brain and Blood N-Glycome Profiling in Alzheimer's Disease and Alzheimer's Disease-Related Dementias
Yu, Lei
Huo, Zhiguang
Yang, Jingyun
Palma-Gudiel, Helena
Boyle, Patricia A.
Schneider, Julie A.
Bennett, David A.
Zhao, Jinying
FRONTIERS IN AGING NEUROSCIENCE, 2021, 13
[50] Gene Expression of Disease-related Genes in Alzheimer's Disease is Impaired by Tau Aggregation
Siano, G.
Varisco, M.
Scarlatti, A.
Caiazza, M. C.
Dunville, K.
Cremisi, F.
Costa, M.
Pancrazi, L.
Di Primio, C.
Cattaneo, A.
JOURNAL OF MOLECULAR BIOLOGY, 2020, 432 (24)

← 1 2 3 4 5 →