An efficient asymmetric synthesis of furofuran lignans: (+)-sesamin and (-)-sesamin

被引：24

作者：

Kim, JC

Kim, KH

Jung, JC

Park, OS ^{[1
]}

机构：

[1] Chungbuk Natl Univ, Coll Nat Sci, Inst Basic Sci, Dept Chem, Chungbuk 361763, South Korea

[2] Univ Mississippi, Dept Med Chem, Sch Pharm, University, MS 38677 USA

来源：

TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 01期

关键词：

D O I：

10.1016/j.tetasy.2005.11.007

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An efficient synthesis of (+)-sesamin 1a and (-)-sesamin 1b is described. The key reactions include highly stereoselective aldol condensation of piperonal 7 with the dianion of chiral oxazolidinone 8, followed by intramolecular ring cyclization of aldol product 11 in high yield. (c) 2005 Published by Elsevier Ltd.

引用

页码：3 / 6

页数：4

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