An efficient asymmetric synthesis of furofuran lignans: (+)-sesamin and (-)-sesamin

被引：24
|
作者：
Kim, JC
Kim, KH
Jung, JC
Park, OS [1 ]
机构：
[1] Chungbuk Natl Univ, Coll Nat Sci, Inst Basic Sci, Dept Chem, Chungbuk 361763, South Korea
[2] Univ Mississippi, Dept Med Chem, Sch Pharm, University, MS 38677 USA
来源：
TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 01期
关键词：
D O I：
10.1016/j.tetasy.2005.11.007
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
An efficient synthesis of (+)-sesamin 1a and (-)-sesamin 1b is described. The key reactions include highly stereoselective aldol condensation of piperonal 7 with the dianion of chiral oxazolidinone 8, followed by intramolecular ring cyclization of aldol product 11 in high yield. (c) 2005 Published by Elsevier Ltd.
引用
收藏
页码：3 / 6
页数：4
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