Synthesis of β-Amino acids via catalyst- and solvent-free aza-Michael reaction

被引：19
|
作者：
Zou Bo [1 ]
Jiang Huan-Feng [1 ]
机构：
[1] S China Univ Technol, Coll Chem, Guangzhou 510640, Guangdong, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2008年 / 26卷 / 07期
关键词：
aza-Michael addition; catalyst-free; solvent-free; alpha; beta-unsaturated compound; beta-amino acid;
D O I：
10.1002/cjoc.200890238
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A safe, environmentally friendly and cost-effective method for the synthesis of beta-amino acid derivatives has been developed. Treatment of alpha,beta-unsaturated compounds with aliphatic amines furnishes beta-amino acid derivatives in good to excellent yields via a catalyst- and solvent-free aza-Michael addition.
引用
收藏
页码：1309 / 1314
页数：6
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