1,1′-Dimethoxy-3,3′-dimethyl-3,3′-(hexane-1,6-diyl)bis(triazen-2-ium-2-olate): a nitric oxide donor

被引:0
|
作者
Zhou, Zhengrong [1 ]
Reynolds, Melissa M. [1 ]
Kampf, Jeff W. [1 ]
Meyerhoff, Mark E. [1 ]
机构
[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
来源
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 2009年 / 65卷
关键词
CHEMISTRY;
D O I
10.1107/S0108270108038420
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The title compound, C10H24N6O4, is the most stable type of nitric oxide (NO) donor among the broad category of discrete N-diazeniumdiolates (NO adducts of nucleophilic small molecule amines). Sitting astride a crystallographic inversion center, the molecule contains a symmetric dimethylhexane1,6-diamine structure bearing two planar O-2-methylated N-diazeniumdiolate functional groups [N(O)=NOMe]. These two groups are parallel to each other and have the potential to release four molecules of NO. The methylated diazeniumdiolate substituent removes the negative charge from the typical N(O) NO- group, thereby increasing the stability of the diazeniumdiolate structure. The crystal was nonmerohedrally twinned by a 180 degrees rotation about the real [101] axis. This is the first N-based bis-diazeniumdiolate compound with a flexible aliphatic main unit to have its structure analyzed and this work demonstrates the utility of stabilizing the N-diazeniumdiolate functional group by methylation.
引用
收藏
页码:O1 / O2
页数:2
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