Synthesis of isochromenones and oxepines via Pd-catalyzed cascade cyclization of alkynes and benzynes involving C-H activation

被引：32
|
作者：
Parthasarathy, Kanniyappan [1 ]
Han, Han [1 ]
Prakash, Chandran [1 ]
Cheng, Chien-Hong [1 ]
机构：
[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30013, Taiwan
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 52期
关键词：
HIGHLY EFFICIENT ROUTE; FUSED POLYCYCLIC AROMATICS; REGIOSELECTIVE SYNTHESIS; ARYL HALIDES; 2+2+2 CYCLOADDITION; BICYCLIC ALKENES; TERMINAL ALKYNES; FACILE SYNTHESIS; BOND ACTIVATION; PALLADIUM;
D O I：
10.1039/c2cc31807e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new method for the synthesis of various isochromen-6-ones and phenanthro[1,10-bc]oxepines via a palladium-catalyzed cascade carbocyclization of 2-iodobenzyl-3-phenylpropiolates and 1-iodo-2-(2-(phenylethynyl) benzyloxy) benzenes with arynes is described. The reactions involve interesting biscarbocyclization of alkynes and benzynes and C-H bond activation.
引用
收藏
页码：6580 / 6582
页数：3
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