Tungstic acid-catalyzed synthesis of 3,3-bis(1H-indol-3-yl)indolin-2-one derivatives

被引:10
|
作者
Patel, Gautam M. [1 ]
Deota, Pradeep T. [1 ]
机构
[1] Maharaja Sayajirao Univ Baroda, Dept Appl Chem, Fac Engn & Technol, Vadodara 390001, India
关键词
indole; isatin; oxindole; tungstic acid; HYDROGEN-PEROXIDE; EFFICIENT; INDOLE; OXINDOLE; ALKALOIDS; ALDEHYDES; ISATIN;
D O I
10.1515/hc-2013-0142
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Tungstic acid was used as a low-cost and readily available heterogeneous catalyst for the synthesis of 3,3-bis(1H-indol-3-yl)indolin-2-one derivatives from indoles. The reaction parameters, including catalyst quantity, solvents, temperature, and time were optimized. The present method has several advantages, such as mild conditions, simple work-up, elimination of anhydrous condition, easy recovery of catalyst and its recyclability as compared with existing methods.
引用
收藏
页码:421 / 424
页数:4
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