short tandem repeats;
HUMCD4;
HUMF13B;
population studies;
Croatia;
D O I:
10.1007/s004140050074
中图分类号:
DF [法律];
D9 [法律];
R [医药、卫生];
学科分类号:
0301 ;
10 ;
摘要:
Population studies were carried out on unrelated individuals of Croatian ancestry. Genomic DNA was amplified by the polymerase chain reaction (PCR) at the polymorphic microsatellite loci HUMCD4 (n = 105 individuals) and HUMF13B (n = 108 individuals). After horizontal polyacrylamide gel electrophoresis followed by silver staining 6 alleles and 12 genotypes were observed for HUMCD4 and 6 alleles and 13 genotypes could be identified for HUMF13B. Data obtained were in concordance with the prediction of Hardy-Weinberg equilibrium. The allele frequency data were compared with Austrian and Italian population samples and no significant deviations between these populations were observed.