Evidence of early life programming of the melanocortin-4 receptor in leptin induced hypertension arising from maternal obesity

被引：0
|
作者：
Samuelsson, Anne-Maj [1 ]
Mullier, Amandine [1 ]
Blasco, Nuria Maicas [1 ]
Coen, Clive W. [1 ]
Taylor, Paul D. [1 ]
Balthasar, Nina [2 ]
Poston, Lucilla [1 ]
机构：
[1] Kings Coll London, Womens Hlth Acad Ctr KHP, Div Womens Hlth, London WC2R 2LS, England
[2] Univ Bristol, Sch Physiol & Pharmacol, Bristol, Avon, England
来源：
JOURNAL OF HUMAN HYPERTENSION | 2015年 / 29卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
PD.05
引用
收藏
页码：644 / 645
页数：2
相关论文
共 43 条
  • [21] Placental Ischemia-Induced Hypertension is Attenuated in Melanocortin-4 Receptor (MC4R)-Deficient Pregnant Rats.
    Spradley, Frank T.
    Granger, Joey P.
    HYPERTENSION, 2018, 72
  • [22] An Evidence-based Framework to Evaluate Melanocortin-4 Receptor (MC4R) Pathway Relevance for Obesity-associated Genes
    Vogel, Megan
    Moeller, Ida
    Garfield, Alastair
    Shah, Bhavik
    HORMONE RESEARCH IN PAEDIATRICS, 2021, 94 (SUPPL 1): : 128 - 129
  • [23] Treatment for Early Onset and Extreme Obesity in Two POMC Deficient Patients: Successful Weight Loss with the Melanocortin-4 Receptor Agonist Setmelanotide
    Kuehnen, Peter
    Clement, Karine
    Gottesdiener, Keith
    Fiedorek, Fred
    van der Ploeg, Lex
    Wiegand, Susanna
    Blankenstein, Oliver
    Grueters, Annette
    Krude, Heiko
    HORMONE RESEARCH IN PAEDIATRICS, 2016, 86 : 62 - 62
  • [24] Successful methylphenidate treatment of early onset extreme obesity in a child with a melanocortin-4 receptor gene mutation and attention deficit/hyperactivity disorder
    Albayrak, Oezguer
    Albrecht, Beate
    Scherag, Susann
    Barth, Nikolaus
    Hinney, Anke
    Hebebrand, Johannes
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 660 (01) : 165 - 170
  • [25] A novel frameshift mutation in the melanocortin-4 receptor gene (MC4R) in two unrelated families with severe early-onset obesity
    Loid, P.
    Pekkinen, M.
    Makitie, R.
    Viljakainen, H.
    Makitie, O.
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2019, 27 : 1837 - 1837
  • [26] Functional characterization of a new human melanocortin-4 receptor homozygous mutation (N72K) that is associated with early-onset obesity
    Delhanty, Patric J. D.
    Bouw, Elise
    Huisman, Martin
    Vervenne, Resie M. L.
    Themmen, Axel P. N.
    van der Lely, Aart Jan
    van den Akker, Erica L. T.
    MOLECULAR BIOLOGY REPORTS, 2014, 41 (12) : 7967 - 7972
  • [27] Functional characterization of a new human melanocortin-4 receptor homozygous mutation (N72K) that is associated with early-onset obesity
    Patric J. D. Delhanty
    Elise Bouw
    Martin Huisman
    Resie M. L. Vervenne
    Axel P. N. Themmen
    Aart Jan van der Lely
    Erica L. T. van den Akker
    Molecular Biology Reports, 2014, 41 : 7967 - 7972
  • [28] Counterintuitive effects of double-heterozygous null melanocortin-4 receptor and leptin genes on diet-induced obesity and insulin resistance in C57BL/6J mice
    Trevaskis, James L.
    Meyer, Emily A.
    Galgani, Jose E.
    Butler, Andrew A.
    ENDOCRINOLOGY, 2008, 149 (01) : 174 - 184
  • [29] Intracellular retention of human melanocortin-4 receptor: A molecular mechanism underlying early-onset obesity in F261S pedigree of Chinese
    Fang, Qi-Chen
    Jia, Wei-Ping
    Cai, Shu-Bing
    Shao, Xin-Yu
    Zhang, Rong
    Wang, Cong-Rong
    Bao, Yu-Qian
    Xiang, Kun-San
    BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2008, 21 (04) : 280 - 285
  • [30] Intracellular Retention of Human Melanocortin-4 Receptor:A Molecular Mechanism Underlying Early-onset Obesity in F261S Pedigree of Chinese
    QI-CHEN FANG
    Shanghai Diabetes Institute
    Shanghai Clinical Center of Diabetes
    BiomedicalandEnvironmentalSciences, 2008, (04) : 280 - 285
12345