Arylglycine-derivative synthesis via oxidative sp3 C-H functionalization of α-amino esters

被引：21
|
作者：
Xu, Zhanwei [1 ]
Yu, Xiaoqiang [1 ]
Feng, Xiujuan [1 ]
Bao, Ming [1 ]
机构：
[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116023, Peoples R China
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 8卷
基金：
中国国家自然科学基金;
关键词：
alpha-amino ester; arylglycine; C-H functionalization; oxidation; synthesis; ASYMMETRIC-SYNTHESIS; ACIDS;
D O I：
10.3762/bjoc.8.178
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method for the synthesis of arylglycine derivatives is described. The oxidative coupling reactions of naphthols and phenols with alpha-amino esters proceeded smoothly in the presence of meta-chloroperoxybenzoic acid as an oxidant under ambient conditions, to produce arylglycine derivatives in satisfactory yields.
引用
收藏
页码：1564 / 1568
页数：5
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