Regulation of CD40L Transgene Expression in Human CAR-T Cells Using FDA Approved Ligands

被引：0

作者：

Weisman, Elizabeth ^{[1
]}

Brideau, Emily ^{[1
]}

Elpek, Kutlu ^{[1
]}

Fleury, Michelle ^{[1
]}

Heller, Scott ^{[1
]}

Reardon, Christopher ^{[1
]}

Schebesta, Michael ^{[1
]}

Sethi, Dhruv ^{[1
]}

Sun, Dexue ^{[1
]}

Tran, Karen ^{[1
]}

Briskin, Michael ^{[1
]}

Gori, Jennifer L. ^{[1
]}

Richardson, Celeste ^{[1
]}

Suri, Vipin ^{[1
]}

Shamah, Steven ^{[1
]}

机构：

[1] Obsidian Therapeut, Cambridge, MA USA

来源：

MOLECULAR THERAPY | 2019年 / 27卷 / 04期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

568

引用

页码：266 / 266

页数：1

共 50 条

[41] CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells
Masayasu Naito
Ursula Hainz
Ute E. Burkhardt
Buyin Fu
Deborah Ahove
Kristen E. Stevenson
Mohini Rajasagi
Baogong Zhu
Anselmo Alonso
Elizabeth Witten
Ken-ichi Matsuoka
Donna Neuberg
Jonathan S. Duke-Cohan
Catherine J. Wu
Gordon J. Freeman
Cancer Immunology, Immunotherapy, 2013, 62 : 347 - 357
[42] Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression
Curran, Kevin J.
Seinstra, Beatrijs A.
Nikhamin, Yan
Yeh, Raymond
Usachenko, Yelena
van Leeuwen, Dayenne G.
Purdon, Terence
Pegram, Hollie J.
Brentjens, Renier J.
MOLECULAR THERAPY, 2015, 23 (04) : 769 - 778
[43] The Role and Mechanism of CD40/CD40L Expression on Different T-Cell Subsets.
Granofszky, N.
Hock, K.
Mahr, B.
Pilat-Michalek, N.
Wekerle, T.
AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 : 418 - 418
[44] Constitutive Expression of CD40L by CAR-Modified Tumor Targeted T Cells Enhances Anti-Tumor Efficacy Both in Vitro and in Vivo
Curran, Kevin J.
Seinstra, Beatrijs
Nikhamin, Yan
Yeh, Raymond
Usachenko, Yelena
Brentjens, Renier J.
BLOOD, 2012, 120 (21)
[45] Collagen synthesis by human intestinal fibroblasts (HIF) is modulated by T-cells through the CD40/CD40 ligand (CD40L) pathway
Vogel, JD
Majors, A
Sturm, A
West, GA
Chakravarti, S
Fiocchi, C
GASTROENTEROLOGY, 2001, 120 (05) : A135 - A135
[46] Quantitation of low level CD40L expression on resting CD4+ve cells
Whale, K.
Mason, S.
Fosatti, G.
Shock, A.
IMMUNOLOGY, 2010, 131 : 164 - 164
[47] CD40L demethylation in CD4 + T cells from women with rheumatoid arthritis
Liao, J.
Liang, G.
Xie, S.
Zhao, H.
Zuo, X.
Li, F.
Chen, J.
Zhao, M.
Chan, T. M.
Lu, Q.
CLINICAL IMMUNOLOGY, 2012, 145 (01) : 13 - 18
[48] Chronic inflammation in atherosclerosis-The CD40L/CD40 axis belongs to dendritic cells and T cells, not platelets
Langer, Harald F.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022, 20 (01) : 3 - 5
[49] CD40L: A new decisive antitumor effector function of CD8+ T cells
Frentsch, A.
Japp, A. Sada
Listopad, J. J.
Stark, R.
Nikolaou, C.
Meinke, S.
Matzmohr, N.
Blankenstein, T.
Thiel, A.
ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 64 - 64
[50] Expression of costimulatory molecules in human neuroblastoma. Evidence that CD40+neuroblastoma cells undergo apoptosis following interaction with CD40L
Airoldi, I
Lualdi, S
Bruno, S
Raffaghello, L
Occhino, M
Gambini, C
Pistoia, V
Corrias, M
BRITISH JOURNAL OF CANCER, 2003, 88 (10) : 1527 - 1536

← 1 2 3 4 5 →