Water-filled Cavities in the Voltage-Sensing Domain of a Potassium Channel Embedded in Lipid Bilayers

被引:0
|
作者
Krepkiy, Dmitriy [1 ]
Mihailescu, Ella [2 ,3 ]
Gawrisch, Klaus [4 ]
White, Stephen H. [2 ,3 ]
Swartz, Kenton J. [1 ]
机构
[1] NINDS, Mol Physiol & Biophys Sect, NIH, Bethesda, MD 20892 USA
[2] Univ Calif Irvine, Dept Physiol & Biophys, Irvine, CA 92717 USA
[3] NIST, Ctr Neutron Res, Gaithersburg, MD 20899 USA
[4] NIAAA, Lab Membrane Biochem & Biophys, Bethesda, MD USA
关键词
D O I
10.1016/j.bpj.2008.12.2494
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
2495-Pos
引用
收藏
页码:483A / 484A
页数:2
相关论文
共 50 条
  • [31] The Isolated Voltage Sensing Domain of the Shaker Potassium Channel forms a Cation Channel
    Zhao, Juan
    Blunck, Rikard
    BIOPHYSICAL JOURNAL, 2017, 112 (03) : 249A - 249A
  • [32] The alignment of a voltage-sensing peptide in dodecylphosphocholine micelles and in oriented lipid bilayers by nuclear magnetic resonance and molecular modeling
    Mattila, K
    Kinder, R
    Bechinger, B
    BIOPHYSICAL JOURNAL, 1999, 77 (04) : 2102 - 2113
  • [33] NMR investigation of the isolated second voltage-sensing domain of human Nav1.4 channel
    Paramonov, A. S.
    Lyukmanova, E. N.
    Myshkin, M. Yu.
    Shulepko, M. A.
    Kulbatskii, D. S.
    Petrosian, N. S.
    Chugunov, A. O.
    Dolgikh, D. A.
    Kirpichnikov, M. P.
    Arseniev, A. S.
    Shenkarev, Z. O.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2017, 1859 (03): : 493 - 506
  • [34] The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel
    Zhao, Juan
    Blunck, Rikard
    ELIFE, 2016, 5
  • [35] Substitutions in the Domain III Voltage-sensing Module Enhance the Sensitivity of an Insect Sodium Channel to a Scorpion β-Toxin
    Song, Weizhong
    Du, Yuzhe
    Liu, Zhiqi
    Luo, Ningguang
    Turkov, Michael
    Gordon, Dalia
    Gurevitz, Michael
    Goldin, Alan L.
    Dong, Ke
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (18) : 15781 - 15788
  • [36] Mutations in the voltage-sensing domain affect the alternative ion permeation pathway in the TRPM3 channel
    Held, Katharina
    Gruss, Fabian
    Aloi, Vincenzo Davide
    Janssens, Annelies
    Ulens, Chris
    Voets, Thomas
    Vriens, Joris
    JOURNAL OF PHYSIOLOGY-LONDON, 2018, 596 (12): : 2413 - 2432
  • [37] Single Channel Studies of the Cation Permeation Pathway of the Shaker Kv Isolated Voltage-Sensing Domain (iVSD)
    Zhao, Juan
    Blunck, Rikard
    BIOPHYSICAL JOURNAL, 2019, 116 (03) : 543A - 543A
  • [38] Atomistic Modeling of Ion Conduction through the Voltage-Sensing Domain of the Shaker K+ Ion Channel
    Wood, Mona L.
    Freites, J. Alfredo
    Tombola, Francesco
    Tobias, Douglas J.
    JOURNAL OF PHYSICAL CHEMISTRY B, 2017, 121 (15): : 3804 - 3812
  • [39] Helical structure and packing orientation of the four transmembrane segments in the voltage-sensing domain of a K+ channel
    Li-Smerin, Y
    Hackos, DH
    Swartz, KJ
    BIOPHYSICAL JOURNAL, 2000, 78 (01) : 97A - 97A
  • [40] Molecular mechanism of the interaction between gating modifier toxin VSTx1 and voltage-sensing domain of potassium KvAP channel revealed by NMR spectroscopy
    Shenkarev, Z. O.
    Lyukmanova, E. N.
    Paramonov, A. S.
    Shingarova, L. N.
    Shulepko, M. A.
    Kirpichnikov, M. P.
    Arseniev, A.
    FEBS JOURNAL, 2014, 281 : 377 - 377