The Role of Cetuximab in the Treatment of Metastatic Colorectal Cancer

被引：0

作者：

Holubec, Lubos ^{[1
]}

Liska, Vaclav ^{[2
]}

Matejka, Vit M. ^{[1
]}

Fiala, Ondrej ^{[1
]}

Dreslerova, Jana ^{[1
]}

Mrazkova, Petra ^{[3
,4
]}

Treska, Vladislav ^{[2
]}

Finek, Jindrich ^{[1
]}

机构：

[1] Charles Univ Prague, Dept Oncol & Radiotherapy, Sch Med, Prague, Czech Republic

[2] Charles Univ Prague, Dept Surg, Sch Med, Prague, Czech Republic

[3] Charles Univ Prague, Dept Radiol, Sch Med, Prague, Czech Republic

[4] Charles Univ Prague, Teaching Hosp Pilsen, Prague, Czech Republic

来源：

ANTICANCER RESEARCH | 2012年 / 32卷 / 09期

关键词：

KRAS; cetuximab; colorectal cancer; liver metastases; review; PLUS IRINOTECAN; 1ST-LINE TREATMENT; COMBINATION CHEMOTHERAPY; NEOADJUVANT CHEMOTHERAPY; LIVER METASTASES; OXALIPLATIN; FLUOROPYRIMIDINE; LEUCOVORIN; RESECTION;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Targeted biological therapy is becoming a standard in personalized medicine for patients with advanced stages of cancer. Treatment with cetuximab, an anti-epidermal growth factor receptor (EGFR) antibody, represents an example of personalized anticancer the for patients with metastatic colorectal cancer and wild (non-mutated) type of the Kirsten rat sarcoma viral oncogene (KRAS). Here the role of cetuximab in treating metastatic colorectal cancer is discussed with a focus on the treatment of hepatic metastases.

引用

页码：4007 / 4011

页数：5

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