Neo-clerodane diterpenoids from Teucrium polium

被引：31
|
作者：
Bedir, E
Tasdemir, D
Çalis, I [1 ]
Zerbe, O
Sticher, O
机构：
[1] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey
[2] Swiss Fed Inst Technol, Dept Pharm, CH-8057 Zurich, Switzerland
来源：
PHYTOCHEMISTRY | 1999年 / 51卷 / 07期
关键词：
Teucrium polium; Lamiaceae; diterpenoids; neo-clerodane derivative; teulolins A; B;
D O I：
10.1016/S0031-9422(99)00052-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new neo-clerodane type diterpenoids, teulolin A (15,16-epoxy-6 beta,7 beta,18,19-tetrahydroxy-neo-cleroda-3(4),13(16),14-trien-20,12(S)-olide, 1) and teulolin B (15,16-epoxy-3 alpha, 6 beta, 7 beta, 18, 19-tetrahydroxy-neo-cleroda-4(18),13(16),14-trien-20,12(S)-olide, 2) were isolated from the aerial parts of Teucrium polium. The structures of 1-2 were proposed on the basis of extensive NMR experiments and molecular modeling studies. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：921 / 925
页数：5
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