CX3CL1 at the crossroad of EGF signals Relevance for the progression of ERBB2+ breast carcinoma

被引：11

作者：

Tardaguila, Manuel ^{[1
]}

Manes, Santos ^{[1
]}

机构：

[1] CSIC, Ctr Nacl Biotecnol, Dept Immunol & Oncol, Madrid, Spain

来源：

ONCOIMMUNOLOGY | 2013年 / 2卷 / 09期

关键词：

chemokine; cross-activation; ERK; fractalkine; inflammation; MAPK; tumor promotion; RECEPTOR TRANSACTIVATION; CHEMOKINE; IDENTIFICATION; FRACTALKINE; THERAPY; CANCER; TARGET;

D O I：

10.4161/onci.25669

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Inflammatory mediators can play a dual role in oncogenesis and tumor progression. CX3CL1, a chemokine previously implicated in natural killer cell- and CD8(+) T cell-mediated antitumor immune responses, has now been identified as a promoter of ERBB2-expressing breast carcinomas as it cross-activates members of the epidermal growth factor receptor family.

引用

页数：3

共 50 条

[41] Expression and analysis of CX3CL1 chemokine and CD57+lymphocytes in oral squamous cell carcinoma and their correlation with clinicopathologic features
Singh, Shivani
Urs, Aadithya B.
Kumar, Priya
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2024, 20 (03) : 770 - 775
[42] Double-faced CX3CL1 enhances lymphangiogenesis-dependent metastasis in an aggressive subclone of oral squamous cell carcinoma
Eain, Htoo Shwe
Kawai, Hotaka
Nakayama, Masaaki
Oo, May Wathone
Ohara, Toshiaki
Fukuhara, Yoko
Takabatake, Kiyofumi
Shan, Quisheng
Soe, Yamin
Ono, Kisho
Nakano, Keisuke
Mizukawa, Nobuyoshi
Iida, Seiji
Nagatsuka, Hitoshi
JCI INSIGHT, 2024, 9 (10)
[43] CX3CL1 in the red bone marrow promotes renal cell carcinoma to metastasize to the spine by involving the Src-related pathway
HU, An-Nan
CHEN, Fan-Cheng
WANG, Ke-Tao
WANG, Zhen-Qing
LIANG, Yun
DONG, Jian
NEOPLASMA, 2022, 69 (03) : 670 - +
[44] The miR-561-5p/CX3CL1 Signaling Axis Regulates Pulmonary Metastasis in Hepatocellular Carcinoma Involving CX3CR1+ Natural Killer Cells Infiltration
Chen, Er-Bao
Zhou, Zheng-Jun
Xiao, Kun
Zhu, Gui-Qi
Yang, Yi
Wang, Biao
Zhou, Shao-Lai
Chen, Qing
Yin, Dan
Wang, Zheng
Shi, Ying-Hong
Gao, Dong-Mei
Chen, Jie
Zhao, Yan
Wu, Wei-Zhong
Fan, Jia
Zhou, Jian
Dai, Zhi
THERANOSTICS, 2019, 9 (16): : 4779 - 4794
[45] Increased circulatory levels of fractalkine (CX3CL1) are associated with inflammatory chemokines and cytokines in individuals with type-2 diabetes
Sindhu S.
Akhter N.
Arefanian H.
Al-Roub A.A.
Ali S.
Wilson A.
Al-Hubail A.
Al-Beloushi S.
Al-Zanki S.
Ahmad R.
Journal of Diabetes & Metabolic Disorders, 16 (1):
[46] The Chemokine CX3CL1 Improves Trastuzumab Efficacy in HER2 Low-Expressing Cancer In Vitro and In Vivo
Dreyer, Tobias F.
Kuhn, Sabine
Stange, Christoph
Heithorst, Nadine
Schilling, Daniela
Jelsma, Jil
Sievert, Wolfgang
Seitz, Stefanie
Stangl, Stefan
Hapfelmeier, Alexander
Noske, Aurelia
Wege, Anja K.
Weichert, Wilko
Ruland, Juergen
Schmitt, Manfred
Dorn, Julia
Kiechle, Marion
Reuning, Ute
Magdolen, Viktor
Multhoff, Gabriele
Bronger, Holger
CANCER IMMUNOLOGY RESEARCH, 2021, 9 (07) : 779 - 789
[47] Urinary IgG, serum CX3CL1 and miRNA-152-3p: as predictors of nephropathy in Egyptian type 2 diabetic patients
Abdou, Aml E.
Anani, Haneya A. A.
Ibrahim, Hanan F.
Ebrahem, Eman Elshohat
Seliem, Nora
Youssef, Eman M., I
Ghoraba, Niveen M.
Hassan, Asmaa S.
Ramadan, Marwa A. A.
Mahmoud, Eman
Issa, Shorouk
Maghraby, Hend M.
Abdelrahman, Eman K.
Hassan, Hala Ali Mohammed
TISSUE BARRIERS, 2022, 10 (03):
[48] Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration
Popovic, Milan
Laumonnier, Yves
Burysek, Ladislav
Syrovets, Tatiana
Simmet, Thomas
JOURNAL OF LEUKOCYTE BIOLOGY, 2008, 84 (01) : 215 - 223
[49] NPAS2 ameliorates myocardial ischaemia/reperfusion injury in rats via CX3CL1 pathways and regulating autophagy
Huang, Jing
Qing, Wan
Pan, Yesheng
AGING-US, 2021, 13 (16): : 20569 - 20584
[50] Chemokine–Chemokine Receptor CCL2–CCR2 and CX3CL1–CX3CR1 Axis May Play a Role in the Aggravated Inflammation in Primary Biliary Cirrhosis
Motoko Sasaki
Masami Miyakoshi
Yasunori Sato
Yasuni Nakanuma
Digestive Diseases and Sciences, 2014, 59 : 358 - 364

← 1 2 3 4 5 →