Predictable removal of anticardiolipin antibody by therapeutic plasma exchange (TPE) in catastrophic antiphospholipid antibody syndrome (CAPS)

被引：0
|
作者：
Zar, T. [1 ]
Kaplan, A. A. [1 ]
机构：
[1] Univ Connecticut, Ctr Hlth, Dept Med, Div Nephrol, Farmington, CT 06030 USA
来源：
CLINICAL NEPHROLOGY | 2008年 / 70卷 / 01期
关键词：
CAPS (catastrophic anti phospholipid antibody syndrome) plasmapheresis; therapeutic plasma exchange; anticardiolipin antibody;
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Catastrophic antiphospholipid antibody syndrome (CAPS) is a rare life-threatening variant of antiphospholipid antibody syndrome (APS), with an associated mortality rate of > 50%. Treatment recommendations are aggressive and consist of intravenous heparin, steroids, immunoglobulins and/or therapeutic plasma exchange (TPE). At present, insufficient data exist to make precise recommendations regarding the most effective therapy for CAPS. Accumulating evidence over recent years is encouraging and may lead to future guidelines. We report predictive and effective removal of pathological anticardiolipin antibody (aCL AB) in a patient with CAPS. The case report and discussion provide valuable insight into aCL AB production and its removal by first-order kinetics using TPE.
引用
收藏
页码：77 / 81
页数：5
相关论文
共 50 条
  • [31] Catastrophic antiphospholipid antibody syndrome associated with ischaemic cardiomyopathy
    Pacella, Jonathan
    Rodriguez-Smith, Jackeline
    Kessler, Haeja
    Mantell, Benjamin S.
    CARDIOLOGY IN THE YOUNG, 2025,
  • [32] Catastrophic antiphospholipid antibody syndrome following initiation of hemodialysis
    Yotsueda H.
    Tsuruya K.
    Tokumoto M.
    Hirakata H.
    Iida M.
    Clinical and Experimental Nephrology, 2005, 9 (4) : 335 - 339
  • [33] A RARE MICROTHROMBI DISEASE: CATASTROPHIC ANTIPHOSPHOLIPID ANTIBODY SYNDROME
    Mohanakrishnan, Balaji Prasad Ellappan
    Holder, Katherine G.
    Tasnim, Saria
    Patel, Manish L.
    Davey-Ranasinghe, Nicole L.
    CHEST, 2022, 162 (04) : 982A - 982A
  • [34] Catastrophic antiphospholipid antibody syndrome in primary systemic sclerosis
    Kane, D
    McSweeney, F
    Swan, N
    Bresnihan, B
    JOURNAL OF RHEUMATOLOGY, 1998, 25 (04) : 810 - 812
  • [35] CRITICAL VASCULAR THROMBOSIS IN PATIENTS WITH ANTIPHOSPHOLIPID ANTICARDIOLIPIN ANTIBODY SYNDROME
    INSKO, EK
    HASKAL, ZJ
    GOWIN, KM
    RADIOLOGY, 1995, 197 : 143 - 143
  • [36] Assessment of the role of anticardiolipin antibody test in diagnosis of the antiphospholipid syndrome
    Harris, EN
    Pierangeli, SS
    THROMBOSIS RESEARCH, 2004, 114 (5-6) : 633 - 633
  • [37] Childhood acute myelomonocytic leukemia (AML-M4) presenting as catastrophic antiphospholipid antibody syndrome (CAPS).
    Orsino, A
    Schneider, R
    DeVeber, G
    Grant, R
    Canning, P
    Carcao, M
    BLOOD, 2003, 102 (11) : 234B - 234B
  • [38] Severe Cardiomyopathy in the Setting of Relapsing Catastrophic Antiphospholipid Antibody Syndrome
    Suryadevara, Sourabh
    Ferrara, Jarrod
    Gore, Joel
    Smith, Craig
    AMERICAN JOURNAL OF MEDICINE, 2015, 128 (05): : E13 - E14
  • [39] Catastrophic antiphospholipid antibody syndrome presenting as severe ischaemic colitis
    Gonzalez Puga, Cristina
    Lendinez Romero, Inmaculada
    Palomeque Jimenez, Antonio
    GASTROENTEROLOGIA Y HEPATOLOGIA, 2017, 40 (10): : 684 - 687
  • [40] Catastrophic Antiphospholipid Antibody Syndrome Presenting As Diffuse Alveolar Hemorrhage
    Bhadriraju, S.
    Kasi, P.
    Trier, H.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187
12345