Genomics is rapidly advancing precision medicine for immunological disorders

被引：27
|
作者：
Zhang, Yu [1 ,2 ,3 ]
Su, Helen C. [1 ,2 ]
Lenardo, Michael J. [2 ,3 ]
机构：
[1] NIAID, Human Immunol Dis Unit, Lab Host Def, NIH, Bethesda, MD 20892 USA
[2] NIAID, Clin Genom Program, NIH, Bethesda, MD 20892 USA
[3] NIAID, Mol Dev Immune Syst Sect, Immunol Lab, NIH, Bethesda, MD 20892 USA
来源：
NATURE IMMUNOLOGY | 2015年 / 16卷 / 10期
关键词：
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; IMMUNE DYSREGULATION; INBORN-ERRORS; GERMLINE MUTATIONS; IMMUNODEFICIENCY; GLYCOSYLATION; DEFICIENCY; GUIDELINES; INFECTION; APOPTOSIS;
D O I：
10.1038/ni.3275
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Advances in human genomics, when validated functionally, can lead to new insights into how the immune system works. Notably, previously unknown mechanisms revealed by genomics can lead to the development of precision medicine unanticipated on the basis of phenotype alone.
引用
收藏
页码：1001 / 1004
页数：4
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