Incorporation of cytochrome C with thin calcium phosphate film formed by electron-beam evaporation

被引：7

作者：

Li, Yan ^{[3
]}

Lee, In-Seop ^{[1
,2
]}

Cui, Fu-Zhai ^{[3
]}

Lin, Zeng ^{[1
,2
]}

Park, Jong-Chul ^{[4
]}

Chung, Sung-Min ^{[5
]}

机构：

[1] Yonsei Univ, Inst Phys Appl Phys, Seoul 120749, South Korea

[2] Yonsei Univ, Atom Scale Surface Sci Res Ctr, Seoul 120749, South Korea

[3] Tsinghua Univ, Dept Mat Sci & Engn, Adv Mat Lab, Beijing 100084, Peoples R China

[4] Yonsei Univ, Coll Med, Dept Med Engn, Seoul 120749, South Korea

[5] Implantium Implant Inst, Seoul 135879, South Korea

来源：

SURFACE & COATINGS TECHNOLOGY | 2008年 / 202卷 / 22-23期

关键词：

Calcium phosphate; Cytochrome C; DPBS; e-beam evaporation; Cyt C-apatite composite layer;

D O I：

10.1016/j.surfcoat.2008.06.082

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Surface properties play a Major role to determine the biocompatibility that is the ability of a material to perform with an appropriate host response in a specific application because biomaterials contact and interact with biological systems. Various methods have been studied to improve the surface properties and farther the osseous intergradation of bone implants. Cytochrome C (cyt C) was immobilized on the thin calcium phosphate films formed by electron-beam evaporation in the form of cyt C-apatite composite layer. The newly formed apatite layer was observed by scanning electron microscopy, and X-ray photoelectron spectroscopy confirmed that cyt C existed in the newly formed layer. Cyt C released from the cyt C-apatite composite layer for at least 10 days in the physiological salt solution. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：5742 / 5745

页数：4

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