NanoWell array-based digital BioChip platform

被引：0
|
作者：
Kawai, Tomoji [1 ]
Lee, Hea Yeon [1 ]
机构：
[1] Osaka Univ, Inst Sci & Ind Res, 8-1 Mihogaoka, Ibaraki, Osaka 5670047, Japan
来源：
MATHEMATICS AND COMPUTERS IN BIOLOGY AND CHEMISTRY | 2008年
关键词：
nanowell (NW) array; biochip; digital; DNA; specific binding; bio-information analysis;
D O I：
暂无
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
We describe the nanometrics geometry of a well-oriented nanowell (NW) array derived from nanofabrication technology which can easily be employed for digital detection with a high S/N ratio, miniaturization, integrated assays and single molecule analysis. In this geometry, the depth and width of the nanosized well can be adjusted to allow for only one or a few biomolecules to enter inside the nanowell and become attached with the self-assembled modified gold surface.
引用
收藏
页码：154 / +
页数：2
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