Metabolite identification by LC-MS: Applications in drug discovery and development

被引：0
|
作者：
Hop, CECA [1 ]
Prakash, C [1 ]
机构：
[1] Dept Pfizer Global Res & Dev, Groton, CT 06340 USA
来源：
IDENTIFICATION AND QUANTIFICATION OF DRUGS, METABOLITES AND METABOLIZING ENZYMES BY LC-MS | 2005年 / 6卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：123 / 158
页数：36
相关论文
共 50 条
  • [11] Identification of a major human urinary metabolite of metolachlor by LC-MS/MS
    Driskell, WJ
    Hill, RH
    BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1997, 58 (06) : 929 - 933
  • [12] Identification of a major human urinary metabolite of alachlor by LC-MS/MS
    Driskell, WJ
    Hill, RH
    Shealy, DB
    Hull, RD
    Hines, CJ
    BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1996, 56 (06) : 853 - 859
  • [13] Identification of a Major Human Urinary Metabolite of Metolachlor by LC-MS/MS
    W. J. Driskell
    R. H. Hill, Jr.
    Bulletin of Environmental Contamination and Toxicology, 1997, 58 : 929 - 933
  • [14] Development of LC-MS/MS and LC-MS/TOF methods to study trends in drug abuse and drug adulteration
    Lynch, K. L.
    Petrie, M. S.
    Wu, A. H. B.
    THERAPEUTIC DRUG MONITORING, 2011, 33 (04) : 470 - 470
  • [15] In vitro DMPK screening in drug discovery, role of LC-MS/MS
    Chu, IH
    Nomeir, AA
    Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS, 2005, 6 : 105 - 122
  • [16] Application of LC-MS and LC-NMR Techniques for Secondary Metabolite Identification
    Richard, Tristan
    Temsamani, Hamza
    Cantos-Villar, Emma
    Monti, Jean-Pierre
    METABOLOMICS COMING OF AGE WITH ITS TECHNOLOGICAL DIVERSITY, 2013, 67 : 67 - 98
  • [17] LC-MS/MS discovery tool for the identification or histone posttranslational modifications
    Galligan, James
    Kingsley, Philip
    Marnett, Lawrence
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [18] Pitfalls in quantitative LC-MS/MS: Metabolite contribution to measured drug concentration
    Jemal, M
    IDENTIFICATION AND QUANTIFICATION OF DRUGS, METABOLITES AND METABOLIZING ENZYMES BY LC-MS, 2005, 6 : 65 - 103
  • [19] In vivo metabolite detection and identification in drug discovery via LC-MS/MS with data-dependent scanning and post-acquisition data mining
    Triolo, A
    Altamura, M
    Dimoulas, T
    Guidi, A
    Lecci, A
    Tramontana, M
    JOURNAL OF MASS SPECTROMETRY, 2005, 40 (12): : 1572 - 1582
  • [20] Applications of LC-MS methodology in the development of pharmaceuticals
    Krstulovic, AM
    Lee, CR
    Firmin, S
    Jacquet, G
    Van Dau, CN
    Tessier, D
    LC GC EUROPE, 2002, 15 (01) : 31 - +
12345