Direct synthesis of γ-substituted phthalides by cyclization of benzyl radicals generated from o-(arylmethyl)benzoic acids

被引：12
|
作者：
Mahmoodi, NO [1 ]
Salehpour, M [1 ]
机构：
[1] Univ Guilan, Dept Chem, Organ Res Lab, Rasht, Iran
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 39卷 / 12期
关键词：
Oxidation; Sodium; Chloride; Organic Chemistry; Benzyl;
D O I：
10.1023/B:RUJO.0000019740.66204.fa
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct oxidation of o-(arylmethyl)benzoic acids with sodium peroxysulfate-copper(II) chloride in water yields gamma-substituted phthalides. The reaction is highly regioselective, and the corresponding gamma-butyrolactones are the only products formed through intermediate stable arylmethyl radicals.
引用
收藏
页码：1760 / 1763
页数：4
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