Direct synthesis of γ-substituted phthalides by cyclization of benzyl radicals generated from o-(arylmethyl)benzoic acids

被引：12

作者：

Mahmoodi, NO ^{[1
]}

Salehpour, M ^{[1
]}

机构：

[1] Univ Guilan, Dept Chem, Organ Res Lab, Rasht, Iran

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 39卷 / 12期

关键词：

Oxidation; Sodium; Chloride; Organic Chemistry; Benzyl;

D O I：

10.1023/B:RUJO.0000019740.66204.fa

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Direct oxidation of o-(arylmethyl)benzoic acids with sodium peroxysulfate-copper(II) chloride in water yields gamma-substituted phthalides. The reaction is highly regioselective, and the corresponding gamma-butyrolactones are the only products formed through intermediate stable arylmethyl radicals.

引用

页码：1760 / 1763

页数：4

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