Genotypic Heterogeneity of Orientia tsutsugamushi in Scrub Typhus Patients and Thrombocytopenia Syndrome Co-infection, Myanmar

被引:102
|
作者
Win, Aye Marlar [1 ]
Yen Thi Hai Nguyen [2 ]
Kim, Yuri [2 ]
Na-Young Ha [2 ]
Kang, Jun-Gu [2 ]
Kim, Hongil [2 ]
San, Bo
Kyaw, Okkar [1 ]
Htike, Wah Win [1 ]
Choi, Dong-Ok [3 ]
Lee, Keun-Hwa [4 ]
Cho, Nam-Hyuk [2 ,5 ,6 ]
机构
[1] Univ Med 1, Yangon, Myanmar
[2] Seoul Natl Univ, Coll Med, 103 Daehak Ro, Seoul 03080, South Korea
[3] Bore Da Biotech, Seongnam, South Korea
[4] Hanyang Univ, Coll Med, Seoul, South Korea
[5] Seoul Natl Univ, Med Res Ctr, Seoul, South Korea
[6] Bundang Hosp, Seoul, South Korea
基金
新加坡国家研究基金会;
关键词
SEVERE FEVER;
D O I
10.3201/eid2608.200135
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Serologic and molecular surveillance of serum collected from 152 suspected scrub typhus patients in Myanmar revealed Orientia tsutsugamushi of genotypic heterogeneity. In addition, potential co-infection with severe fever with thrombocytopenia syndrome virus was observed in 5 (3.3%) patients. Both scrub typhus and severe fever with thrombocytopenia syndrome are endemic in Myanmar.
引用
收藏
页码:1878 / 1881
页数:4
相关论文
共 50 条
  • [41] Comparison of a rapid diagnostic test and microimmunofluorescence assay for detecting antibody to Orientia tsutsugamushi in scrub typhus patients in China
    Zhang, Lijuan
    He, Si
    Wang, Shiwen
    Yu, Huilan
    Li, Xuemei
    Zhang, Derong
    Pan, Lei
    Yu, Qiang
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2011, 4 (08) : 666 - 668
  • [42] Scrub Typhus and Dengue Co-infection in an Adolescent Girl: A Diagnostic Challenge
    Kannabiran, Rajesh Kanna
    Banerjee, Arjun
    Jyothi, Lakshmi
    Reddy, Mounika
    Narang, Rahul
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (06)
  • [43] Co-Infection of Scrub Typhus and Human Granulocytic Anaplasmosis in Korea, 2006
    Kim, Jeong-Han
    Lee, Chang-Seop
    Moon, Chisook
    Kwak, Yee Gyung
    Kim, Baek-Nam
    Kim, Eu Suk
    Kang, Jae Myung
    Park, Wan Beom
    Oh, Myoung-don
    Park, Sang-Won
    JOURNAL OF KOREAN MEDICAL SCIENCE, 2019, 34 (39)
  • [44] Use of chimeric antibodies as positive controls in an enzyme-linked immunosorbent assay for diagnosis of scrub typhus (Infection by Orientia tsutsugamushi)
    Jones, Martina L.
    Barnard, Ross T.
    CLINICAL AND VACCINE IMMUNOLOGY, 2007, 14 (10) : 1307 - 1310
  • [45] Evidence of natural infection of Orientia tsutsugamushi in vectors and animal hosts - Risk of scrub typhus transmission to humans in Puducherry, South India
    Devaraju, Panneer
    Arumugam, Bhuvaneswari
    Mohan, Iswaryalakshmi
    Paraman, Mariselvam
    Ashokkumar, Mathivanan
    Kasinathan, Gunasekaran
    Purushothaman, Jambulingam
    INDIAN JOURNAL OF PUBLIC HEALTH, 2020, 64 (01) : 27 - 31
  • [46] Diagnostic Accuracy of a Loop-Mediated Isothermal PCR Assay for Detection of Orientia tsutsugamushi during Acute Scrub Typhus Infection
    Paris, Daniel H.
    Blacksell, Stuart D.
    Nawtaisong, Pruksa
    Jenjaroen, Kemajittra
    Teeraratkul, Achara
    Chierakul, Wirongrong
    Wuthiekanun, Vanaporn
    Kantipong, Pacharee
    Day, Nicholas P. J.
    PLOS NEGLECTED TROPICAL DISEASES, 2011, 5 (09):
  • [47] Genetic recombination of Orientia tsutsugamushi strains from scrub typhus patients in Guangxi, Southwest China, and the analysis of clinical features
    Lu, Miao
    Zhou, Dongsheng
    Xie, Siyan
    Wang, Yumeng
    Jiang, Liyan
    Wang, Wen
    Jiang, Weiping
    Zhou, Qiuling
    Wang, Caifeng
    Zheng, Chanjun
    Huang, Di
    Yang, Hualing
    Gong, Lina
    Chen, Huoying
    Li, Kun
    MICROBES AND INFECTION, 2023, 25 (05)
  • [48] Activation of Indoleamine 2,3-Dioxygenase in Patients with Scrub Typhus and Its Role in Growth Restriction of Orientia tsutsugamushi
    Prachason, Thanavadee
    Konhan, Kanittha
    Pongnarin, Piyapat
    Chatsiricharoenkul, Somruedee
    Suputtamongkol, Yupin
    Limwongse, Chanin
    PLOS NEGLECTED TROPICAL DISEASES, 2012, 6 (07):
  • [49] Clinical, laboratory profile and molecular characterization of Orientia tsutsugamushi among fatal scrub typhus patients from Karnataka, India
    Chunduru, Kiran
    Manoj, A. R.
    Poornima, Subhadra
    Hande, Manjunatha H.
    Devaki, Ramakrishna
    Varghese, George M.
    Saravu, Kavitha
    INFECTIOUS DISEASES, 2024, 56 (03) : 220 - 229
  • [50] Longevity of antibody and T-cell responses against outer membrane antigens of Orientia tsutsugamushi in scrub typhus patients
    Ha, Na-Young
    Kim, Yuri
    Min, Chan-Ki
    Kim, Hong-Il
    Yen, Nguyen Thi Hai
    Choi, Myung-Sik
    Kang, Jae-Seung
    Kim, Yeon-Sook
    Cho, Nam-Hyuk
    EMERGING MICROBES & INFECTIONS, 2017, 6