Icariin-Loaded TiO2 Nanotubes for Regulation of the Bioactivity of Bone Marrow Cells
被引:5
|
作者:
Zhang, Yanli
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R ChinaSouthern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China
Zhang, Yanli
[1
]
Liu, Chundong
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Zhujiang Hosp, Dept Stomatol, Guangzhou, Guangdong, Peoples R ChinaSouthern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China
Liu, Chundong
[2
]
Chen, Liangjiao
论文数: 0引用数: 0
h-index: 0
机构:
Guangzhou Med Univ, Stomatol Hosp, Guangzhou Inst Oral Dis, Key Lab Oral Med, Guangzhou 510140, Guangdong, Peoples R ChinaSouthern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China
Chen, Liangjiao
[3
]
论文数: 引用数:
h-index:
机构:
Chen, Aijie
[1
]
Feng, Xiaoli
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R ChinaSouthern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China
Feng, Xiaoli
[1
]
Shao, Longquan
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R ChinaSouthern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China
Shao, Longquan
[1
]
机构:
[1] Southern Med Univ, Nanfang Hosp, Guangzhou 510515, Guangdong, Peoples R China
[2] Southern Med Univ, Zhujiang Hosp, Dept Stomatol, Guangzhou, Guangdong, Peoples R China
[3] Guangzhou Med Univ, Stomatol Hosp, Guangzhou Inst Oral Dis, Key Lab Oral Med, Guangzhou 510140, Guangdong, Peoples R China
To explore the effects of icariin on the biocompatibility of dental implants, icariin- (ICA-) loaded TiO2 nanotubes were fabricated on Ti substrates via anodic oxidation and physical absorption. The surface characteristics of the specimens were monitored by field emission scanning electron microscopy (FE-SEM), X-ray diffractometry (XRD), contact angle measurements (CA), and high pressure liquid chromatography. Additionally, the activities of bone marrow cells, such as cytoskeletal, proliferative activities, mineralization, and osteogenesis-related gene expression on the substrates were investigated in detail. The characterization results demonstrated that ICA-loaded TiO2 nanotubes were successfully fabricated and the hydrophilicity of these TiO2 nanotubes was significantly higher than that of the pure Ti groups. The results also showed that ICA-loaded TiO2 nanotubes might not have enhanced effects on cell proliferation and ALP expression. However, it seemed to significantly promote differentiation of bone marrow cells, demonstrated by enhancing the formation of mineralized nodule and the upregulation of the gene expression such as OC, BSP, OPN, and COL-1. The results indicated that ICA-loaded TiO2 nanotubes can modulate bioactivity of bone marrow cells, which is promising for potential applications in the orthopedics field.
机构:
Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Lab Microelect Mat & Technol, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Ding, Dongyan
Ning, Congqin
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Ning, Congqin
Huang, Lin
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Lab Microelect Mat & Technol, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Huang, Lin
Jin, Fangchun
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Med, Peoples Hosp 9, Shanghai 200011, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Jin, Fangchun
Hao, Yongqiang
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Med, Peoples Hosp 9, Shanghai 200011, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Hao, Yongqiang
Bai, Shuo
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Lab Microelect Mat & Technol, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Bai, Shuo
Li, Yan
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Lab Microelect Mat & Technol, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Li, Yan
Li, Ming
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Lab Microelect Mat & Technol, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
Li, Ming
Mao, Dali
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Lab Microelect Mat & Technol, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R ChinaChinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
机构:
Shanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R ChinaShanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R China
Wu, Zhi
Wang, Sanguo
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab Performance Ceram & Superfine Micro, 1295 Dingxi Rd, Shanghai 200050, Peoples R ChinaShanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R China
Wang, Sanguo
Chang, Jiang
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R China
Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab Performance Ceram & Superfine Micro, 1295 Dingxi Rd, Shanghai 200050, Peoples R ChinaShanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R China
Chang, Jiang
Huan, Zhiguang
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab Performance Ceram & Superfine Micro, 1295 Dingxi Rd, Shanghai 200050, Peoples R ChinaShanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R China
Huan, Zhiguang
Li, Haiyan
论文数: 0引用数: 0
h-index: 0
机构:
Shanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R ChinaShanghai Jiao Tong Univ, Sch Biomed Engn, Med X Res Inst, Shanghai 200030, Peoples R China
机构:
China National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, JiangxiChina National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, Jiangxi
Wang Z.
Shen Z.
论文数: 0引用数: 0
h-index: 0
机构:
China National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, JiangxiChina National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, Jiangxi
Shen Z.
Li Y.
论文数: 0引用数: 0
h-index: 0
机构:
China National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, JiangxiChina National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, Jiangxi
Li Y.
Zuo J.
论文数: 0引用数: 0
h-index: 0
机构:
China National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, JiangxiChina National Light Industry Key Laboratory of Functional Ceramic Materials, School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403, Jiangxi