OVEREXPRESSION OF ISOCITRATE DEHYDROGENASE 1/2 (IDH1/2) MUTANT PROTEIN RENDERS GLIOMA CELLS MORE SENSITIVE TO RADIATION

被引：0
|
作者：
Li, Sichen [1 ]
Chou, Arthur P. [1 ]
Chen, Weidong [1 ]
Chen, Ruihuan [2 ]
Deng, Yuzhong [2 ]
Phillips, Heidi S. [2 ]
Faull, Kym F. [1 ]
Cloughesy, Timothy [1 ]
Liau, Linda M. [1 ]
Lai, Albert [1 ]
机构：
[1] Univ Calif Los Angeles, Los Angeles, CA USA
[2] Genentech Inc, San Francisco, CA 94080 USA
来源：
NEURO-ONCOLOGY | 2012年 / 14卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：129 / 129
页数：1
相关论文
共 50 条
  • [21] IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat
    Sears, Thomas K.
    Horbinski, Craig M.
    Woolard, Kevin D.
    JOURNAL OF NEURO-ONCOLOGY, 2021, 154 (02) : 159 - 170
  • [22] IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat
    Thomas K. Sears
    Craig M. Horbinski
    Kevin D. Woolard
    Journal of Neuro-Oncology, 2021, 154 : 159 - 170
  • [23] Metabolic reprogramming of pyruvate dehydrogenase is essential for the proliferation of glioma cells expressing mutant IDH1
    Viswanath, Pavithra
    Ronen, Sabrina M.
    MOLECULAR & CELLULAR ONCOLOGY, 2016, 3 (02)
  • [24] Biochemical, Cellular, and Biophysical Characterization of a Potent Inhibitor of Mutant Isocitrate Dehydrogenase IDH1
    Davis, Mindy I.
    Gross, Stefan
    Shen, Min
    Straley, Kimberly S.
    Pragani, Rajan
    Lea, Wendy A.
    Popovici-Muller, Janeta
    DeLaBarre, Byron
    Artin, Erin
    Thorne, Natasha
    Auld, Douglas S.
    Li, Zhuyin
    Dang, Lenny
    Boxer, Matthew B.
    Simeonov, Anton
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (20) : 13717 - 13725
  • [25] MUTANT ISOCITRATE DEHYDROGENASE 1 (IDH1) INHIBITOR SYC-435 SYNERGISTICALLY PROLONGS ANIMAL SURVIVAL WITH STANDARD THERAPIES IN PATIENT-DERIVED IDH1 MUTANT GLIOMA XENOGRAFT MOUSE MODELS
    Kogiso, Mari
    Qi, Lin
    Zhang, Huiyuan
    Braun, Frank
    Du, Yuchen
    Huang, Yulun
    Lindsay, Holly
    Zhao, Sibo
    Injac, Sarah
    Liu, Zhen
    Baxter, Patricia
    Su, Jack
    Perlaky, Laszlo
    Parsons, D. Will
    Chintagumpala, Murali
    Adesina, Adekunle
    Wang, Jialiang
    Song, Yongcheng
    Li, Xiao-Nan
    NEURO-ONCOLOGY, 2017, 19 : 74 - 74
  • [26] Isocitrate Dehydrogenase 1 (IDH1)R132H Mutation Is Not Detected in Angiocentric Glioma
    Raghunathan, A.
    Olar, A.
    Vogel, H.
    Parker, J. R.
    Coventry, S. C.
    Debski, R.
    Albarracin, C. T.
    Aldape, K. D.
    Cahill, D. P.
    Powell, S. Z.
    Fuller, G. N.
    MODERN PATHOLOGY, 2011, 24 : 384A - 384A
  • [27] Isocitrate Dehydrogenase (IDH1/IDH2) Mutation Types and Frequency in Periosteal Cartilaginous Tumors
    Carter, J. M.
    Voss, J. S.
    Kipp, B. R.
    Wenger, D. E.
    Inwards, C. Y.
    MODERN PATHOLOGY, 2013, 26 : 10A - 10A
  • [28] Isocitrate Dehydrogenase 1 (IDH1) R132H Mutation Is Not Detected in Angiocentric Glioma
    Raghunathan, A.
    Olar, A.
    Vogel, H.
    Parker, J. R.
    Coventry, S. C.
    Debski, R.
    Albarracin, C. T.
    Aldape, K. D.
    Cahill, D. P.
    Powell, S. Z.
    Fuller, G. N.
    LABORATORY INVESTIGATION, 2011, 91 : 384A - 384A
  • [29] Non-small cell lung cancers with isocitrate dehydrogenase 1 or 2 (IDH1/2) mutations
    Toth, Laura N.
    de Abreu, Francine B.
    Tafe, Laura J.
    HUMAN PATHOLOGY, 2018, 78 : 138 - 143
  • [30] Inhibitors of mutant IDH1 and IDH2
    Pamela Feliciano
    Nature Genetics, 2013, 45 (5) : 477 - 477
12345