Prognostic Factors in Pediatric Acute Myeloid Leukemia

被引：28
|
作者：
Radhi, Mohamed [1 ]
Meshinchi, Soheil [2 ]
Gamis, Alan [1 ]
机构：
[1] Childrens Mercy Hosp, Kansas City, MO 64108 USA
[2] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
来源：
CURRENT HEMATOLOGIC MALIGNANCY REPORTS | 2010年 / 5卷 / 04期
关键词：
AML; Children; Cytogenetics; Molecular; Response; Prognosis;
D O I：
10.1007/s11899-010-0060-z
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Acute myeloid leukemia (AML), a heterogeneous group of diseases with variable responses to the same therapy, comprises nearly a quarter of childhood acute leukemias. Although historically very few prognostic markers have been incorporated into therapeutic decision making in AML, recent advances in technology have enabled identification of numerous factors associated with disease outcome. This review provides a detailed analysis of most clinically relevant factors associated with disease outcome in childhood AML.
引用
收藏
页码：200 / 206
页数：7
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