Pharmacologic Treatment of Bipolar Disorder in Children and Adolescents

被引:18
|
作者
Goldstein, Benjamin I. [1 ,2 ]
Sassi, Roberto [3 ]
Diler, Rasim S. [4 ]
机构
[1] Univ Toronto, Fac Med, Sunnybrook Hlth Sci Ctr, Dept Psychiat, Toronto, ON M4N 3M5, Canada
[2] Univ Toronto, Fac Med, Sunnybrook Hlth Sci Ctr, Dept Pharmacol, Toronto, ON M4N 3M5, Canada
[3] McMaster Univ, Fac Hlth Sci, Dept Psychiat & Behav Neurosci, Hamilton, ON, Canada
[4] Univ Pittsburgh, Sch Med, Western Psychiat Inst & Clin, Pittsburgh, PA USA
关键词
Bipolar; Manic; Psychopharmacotherapy; Antipsychotics; Mood stabiliziers; Comorbidities; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; OPEN-LABEL TRIAL; PLACEBO-CONTROLLED TRIAL; DEFICIT HYPERACTIVITY DISORDER; TREATMENT ENHANCEMENT PROGRAM; WEEKLY SYMPTOMATIC STATUS; SUBSTANCE USE DISORDERS; SUPPLEMENT NCS-A; DIVALPROEX SODIUM; DOUBLE-BLIND;
D O I
10.1016/j.chc.2012.07.004
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
This review focuses mainly on published articles regarding the treatment of school-aged children and adolescents with pediatric bipolar disorder. In light of systematic reviews, large randomized controlled trial data are emphasized wherever possible. This review addresses the treatment of acute manic/mixed episodes, including combination treatment, the preliminary literature regarding bipolar depression among youth, treatment in the face of comorbid conditions, and maintenance treatment. Suggestions regarding future directions are offered. A clinical vignette describing a teen with bipolar disorder is presented and bipolar medications, dosing, efficacy, side effects, contraindications, and succinct comments on each medication are summarized.
引用
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页码:911 / +
页数:30
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