Mutation Analyses Of The Critical Regions For The Voltage And [ATP] Dependent "Gating" Of P2X2 Receptor Channel

被引：0
|
作者：
Keceli, Batu [1 ]
Fujiwara, Yuichiro [2 ]
Kubo, Yoshihiro [1 ]
机构：
[1] Natl Inst Physiol Sci, Div Biophys & Neurobiol, Okazaki, Aichi, Japan
[2] Osaka Univ, Grad Sc Fac Med, Dept Integrat Physiol, Osaka, Japan
来源：
BIOPHYSICAL JOURNAL | 2009年 / 96卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2008.12.2504
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
2504-Pos
引用
收藏
页码：485A / 485A
页数：1
相关论文
共 50 条
  • [21] Desensitization of P2X2 receptor/channel pore mutants
    Nakazawa, K
    Ohno, Y
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2004, 495 (01) : 27 - 33
  • [22] Ectodomain Movements of an ATP-gated Ion Channel ( P2X2 Receptor) Probed by Disulfide Locking*
    Stelmashenko, Olga
    Compan, Vincent
    Browne, Liam E.
    North, R. Alan
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (14) : 9909 - 9917
  • [23] Agonist trapped in ATP-binding sites of the P2X2 receptor
    Jiang, Ruotian
    Lemoine, Damien
    Martz, Adeline
    Taly, Antoine
    Gonin, Sophie
    de Carvalho, Lia Prado
    Specht, Alexandre
    Grutter, Thomas
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (22) : 9066 - 9071
  • [24] P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP
    Cockayne, DA
    Dunn, PM
    Zhong, Y
    Rong, WF
    Hamilton, SG
    Knight, GE
    Ruan, HZ
    Ma, B
    Yip, P
    Nunn, P
    McMahon, SB
    Burnstock, G
    Ford, APDW
    JOURNAL OF PHYSIOLOGY-LONDON, 2005, 567 (02): : 621 - 639
  • [25] Analyses of the signal flow and subunits' contribution in the P2X2 trimer upon voltage- and [ATP]-dependent activation by three tandem repeat constructs
    Keceli, Batu
    Kubo, Yoshihiro
    NEUROSCIENCE RESEARCH, 2011, 71 : E316 - E316
  • [26] Mutation of the ATP-gated P2X2 receptor leads to progressive hearing loss and increased susceptibility to noise
    Yan, Denise
    Zhu, Yan
    Walsh, Tom
    Xie, Dinghua
    Yuan, Huijun
    Sirmaci, Asli
    Fujikawa, Taro
    Wong, Ann Chi Yan
    Loh, Tze L.
    Du, Lilin
    Grati, M'hamed
    Vlajkovic, Srdjan M.
    Blanton, Susan
    Ryan, Allen F.
    Chen, Zheng-Yi
    Thorne, Peter R.
    Kachar, Bechara
    Tekin, Mustafa
    Zhao, Hong-Bo
    Housley, Gary D.
    King, Mary-Claire
    Liu, Xue Z.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (06) : 2228 - 2233
  • [27] Ligand Binding and Gating in human P2X2 Receptors
    Bruenings, X.
    Schwede, F.
    Schmauder, R.
    Benndorf, K.
    Sattler, C.
    ACTA PHYSIOLOGICA, 2022, 236 : 477 - 477
  • [28] Identification of a distinct desensitisation gate in the ATP-gated P2X2 receptor
    Stavrou, Anastasios
    Evans, Richard J.
    Schmid, Ralf
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 523 (01) : 190 - 195
  • [29] High-Resolution Structures of the Human P2X2 Receptor e an ATP-gated Ion Channel
    Westermann, Franka G.
    Oken, Adam C.
    Mueller, Christa E.
    Mansoor, Steven E.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2025, 392 (03):
  • [30] Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor
    Jiang, Ruotian
    Taly, Antoine
    Lemoine, Damien
    Martz, Adeline
    Specht, Alexandre
    Grutter, Thomas
    CHANNELS, 2012, 6 (05) : 398 - 402
12345