MEPICIDES: POTENT INHIBITORS OF ISOPRENOID METABOLISM IN PLASMODIUM FALCIPARUM

被引:0
|
作者
Edwards, Rachel L. [1 ]
Brothers, Robert C. [2 ]
Kumar, T. R. S. [3 ]
Wang, Xu [2 ]
Maron, Maxim I. [4 ]
Ziniel, Peter D. [5 ]
Tsang, Patricia S. [6 ]
Williamson, Kim C. [5 ]
Fidock, David A. [3 ]
Dowd, Cynthia S. [2 ]
John, Audrey R. Odom [1 ]
机构
[1] Washington Univ, St Louis, MO USA
[2] George Washington Univ, Washington, DC USA
[3] Columbia Univ, New York, NY USA
[4] Loyola Univ, Chicago, IL 60611 USA
[5] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA
[6] NIH, Bldg 10, Bethesda, MD 20892 USA
来源
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2017年 / 97卷 / 05期
关键词
D O I
暂无
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
986
引用
收藏
页码:306 / 306
页数:1
相关论文
共 50 条
  • [21] Ligands of the peripheral benzodiazepine receptor are potent inhibitors of Plasmodium falciparum and Toxoplasma gondii in vitro
    Dzierszinski, F
    Coppin, A
    Mortuaire, M
    Dewailly, E
    Slomianny, C
    Ameisen, JC
    DeBels, F
    Tomavo, S
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (10) : 3197 - 3207
  • [22] Inhibitors of Protein Targets of Plasmodium falciparum
    Oranusi, Solomon Uche
    Mameh, Emmanuel Ojochegbe
    Oyegbade, Samuel Adeniyi
    Balogun, Daniel Oluwatobiloba
    Aririguzoh, Victoria-Grace Onyekachi
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2024,
  • [23] Identification of potential inhibitors of casein kinase 2 alpha of Plasmodium falciparum with potent in vitro activity
    Tomaz, Kaira C. P.
    Tavella, Tatyana A.
    Borba, Joyce V. B.
    Salazar-Alvarez, Luis C.
    Levandoski, Joao E.
    Mottin, Melina
    Sousa, Bruna K. P.
    Moreira-Filho, Jose T.
    Almeida, Vitor M.
    Clementino, Leandro C.
    Bourgard, Catarina
    Massirer, Katlin B.
    Counago, Rafael M.
    Andrade, Carolina H.
    Sunnerhagen, Per
    Bilsland, Elizabeth
    Cassiano, Gustavo C.
    Costa, Fabio T. M.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2023, 67 (11)
  • [24] Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated
    Spry, Christina
    Macuamule, Cristiano
    Lin, Zhiyang
    Virga, Kristopher G.
    Lee, Richard E.
    Strauss, Erick
    Saliba, Kevin J.
    PLOS ONE, 2013, 8 (02):
  • [25] MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase
    Wang, Xu
    Edwards, Rachel L.
    Ball, Haley S.
    Heidel, Kenneth M.
    Brothers, Robert C.
    Johnson, Claire
    Haymond, Amanda
    Girma, Misgina
    Dailey, Allyson
    Roma, Jose Santinni
    Boshoff, Helena I.
    Osbourn, Damon M.
    Meyers, Marvin J.
    Couch, Robin D.
    Odom John, Audrey R.
    Dowd, Cynthia S.
    ACS INFECTIOUS DISEASES, 2023, 9 (07): : 1387 - 1395
  • [26] G-Quadruplex ligands: Potent inhibitors of telomerase activity and cell proliferation in Plasmodium falciparum
    Calvo, E. P.
    Wasserman, M.
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2016, 207 (01) : 33 - 38
  • [27] Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library
    Carroll, CD
    Patel, H
    Johnson, TO
    Guo, T
    Orlowski, M
    He, ZM
    Cavallaro, CL
    Guo, J
    Oksman, A
    Gluzman, IY
    Connelly, J
    Chelsky, D
    Goldberg, DE
    Dolle, RE
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (17) : 2315 - 2320
  • [28] Structural Plasticity of Plasmodium falciparum Plasmepsin X to Accommodate Binding of Potent Macrocyclic Hydroxyethylamine Inhibitors
    Withers-Martinez, Chrislaine
    George, Roger
    Ogrodowicz, Roksana
    Kunzelmann, Simone
    Purkiss, Andrew G.
    Kjaer, Svend
    Walker, Philip A.
    Kovada, Vadims
    Jirgensons, Aigars
    Blackman, Michael J.
    JOURNAL OF MOLECULAR BIOLOGY, 2025, 437 (10)
  • [29] Potent inhibitors of Plasmodium phospholipid metabolism with a broad spectrum of in vitro antimalarial activities
    Ancelin, ML
    Calas, M
    Vidal-Sailhan, V
    Herbuté, S
    Ringwald, P
    Vial, HJ
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (08) : 2590 - 2597
  • [30] Targeting the redox metabolism of Plasmodium falciparum
    Nepveu, Francoise
    Turrini, Francesco
    FUTURE MEDICINAL CHEMISTRY, 2013, 5 (16) : 1993 - 2006