Propagation of a transmissible cytotoxic activity on cultures of human peripheral blood lymphocytes

被引：0
|
作者：
Portolani, Marinella [1 ]
Beretti, Francesca [1 ]
Bartoletti, Anna M. [1 ]
Pietrosemoli, Paola [1 ]
Salvioli, Stefano [2 ,3 ]
Franceschi, Claudio [2 ,3 ,4 ]
Sena, Paola [5 ]
De Pol, Anto [5 ]
机构：
[1] Univ Hosp Modena & Reggio Emilia, Dept Lab Med, Ctr Diag Viral Dis, I-41100 Modena, Italy
[2] Univ Bologna, Dept Expt Pathol, I-40126 Bologna, Italy
[3] Interdepartmental Ctr L Galvani CIG, Bologna, Italy
[4] INRCA, Dept Gerontol Sci, I-60121 Ancona, Italy
[5] Univ Modena & Reggio Emilia, Dept Anat & Histol, Modena, Italy
来源：
NEW MICROBIOLOGICA | 2008年 / 31卷 / 03期
关键词：
human preripheral blood lymphocytes; transmissible cytotoxicity; misfolded proteins;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Positive results were attained when human peripheral blood lymphocytes (PBLs) were investigated for their ability to propagate a transmissible cytotoxic activity (TCA) isolated on VERO cell cultures from a sample of cerebrospinal fluid (CSF) drawn from a woman with ischemic brain injury. In consideration of this finding it can be assumed that "in vivo" blood lymphocytes contributed to give rise to the TCA detected "in vitro" in the CSF inoculum.
引用
收藏
页码：417 / 422
页数：6
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