Propagation of a transmissible cytotoxic activity on cultures of human peripheral blood lymphocytes

被引：0
|
作者：
Portolani, Marinella [1 ]
Beretti, Francesca [1 ]
Bartoletti, Anna M. [1 ]
Pietrosemoli, Paola [1 ]
Salvioli, Stefano [2 ,3 ]
Franceschi, Claudio [2 ,3 ,4 ]
Sena, Paola [5 ]
De Pol, Anto [5 ]
机构：
[1] Univ Hosp Modena & Reggio Emilia, Dept Lab Med, Ctr Diag Viral Dis, I-41100 Modena, Italy
[2] Univ Bologna, Dept Expt Pathol, I-40126 Bologna, Italy
[3] Interdepartmental Ctr L Galvani CIG, Bologna, Italy
[4] INRCA, Dept Gerontol Sci, I-60121 Ancona, Italy
[5] Univ Modena & Reggio Emilia, Dept Anat & Histol, Modena, Italy
来源：
NEW MICROBIOLOGICA | 2008年 / 31卷 / 03期
关键词：
human preripheral blood lymphocytes; transmissible cytotoxicity; misfolded proteins;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Positive results were attained when human peripheral blood lymphocytes (PBLs) were investigated for their ability to propagate a transmissible cytotoxic activity (TCA) isolated on VERO cell cultures from a sample of cerebrospinal fluid (CSF) drawn from a woman with ischemic brain injury. In consideration of this finding it can be assumed that "in vivo" blood lymphocytes contributed to give rise to the TCA detected "in vitro" in the CSF inoculum.
引用
收藏
页码：417 / 422
页数：6
相关论文
共 50 条
  • [1] SUPPRESSOR ACTIVITY IN PHA CULTURES OF HUMAN PERIPHERAL-BLOOD LYMPHOCYTES
    WINGER, LA
    NOWELL, PC
    FEDERATION PROCEEDINGS, 1976, 35 (03) : 435 - 435
  • [2] MITOGENIC ACTIVITY OF TUBERCULIN FRACTIONS IN CULTURES OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES
    HEILMAN, D
    MCFARLAN.W
    FEDERATION PROCEEDINGS, 1966, 25 (2P1) : 549 - &
  • [3] TRANSFORMATION OF LYMPHOCYTES IN CULTURES OF HUMAN PERIPHERAL BLOOD
    TANAKA, Y
    STOHLMAN, F
    BRECHER, G
    EPSTEIN, LB
    BLOOD, 1963, 22 (05) : 614 - &
  • [4] TARGETED CYTOTOXIC-CELLS IN HUMAN PERIPHERAL-BLOOD LYMPHOCYTES
    GARRIDO, MA
    PEREZ, P
    TITUS, JA
    VALDAYO, MJ
    WINKLER, DF
    BARBIERI, SA
    WUNDERLICH, JR
    SEGAL, DM
    JOURNAL OF IMMUNOLOGY, 1990, 144 (08): : 2891 - 2898
  • [5] Genotoxic and cytotoxic effects of flumetralin in human peripheral blood lymphocytes in vitro
    Kocaman, Ayse Yavuz
    Bucak, Sevcan
    TOXICOLOGY AND INDUSTRIAL HEALTH, 2016, 32 (12) : 1927 - 1934
  • [6] Genotoxic and cytotoxic effects of doxycycline in cultured human peripheral blood lymphocytes
    Sekeroglu, Zulal Atli
    Afan, Feridun
    Sekeroglu, Vedat
    DRUG AND CHEMICAL TOXICOLOGY, 2012, 35 (03) : 334 - 340
  • [7] The in vitro genotoxic and cytotoxic effects of remeron on human peripheral blood lymphocytes
    Tazehkand, Mostafa Norizadeh
    Topaktas, Mehmet
    DRUG AND CHEMICAL TOXICOLOGY, 2015, 38 (03) : 266 - 271
  • [8] Genotoxic and cytotoxic effects of polyethylene microplastics on human peripheral blood lymphocytes
    Cobanoglu, Hayal
    Belivermis, Murat
    Sikdokur, Ercan
    Kilic, Onder
    Cayir, Akin
    CHEMOSPHERE, 2021, 272
  • [9] MECHANISMS OF SUPPRESSIVE ACTIVITY IN PHA CULTURES OF PERIPHERAL-BLOOD LYMPHOCYTES
    WINGER, L
    NOWELL, P
    DANIELE, R
    FEDERATION PROCEEDINGS, 1978, 37 (06) : 1356 - 1356
  • [10] Research of telomerase activity in lymphocytes of human peripheral blood
    School of Information Science and Engineering, Northeastern University, Shenyang 110819, China
    Dongbei Daxue Xuebao, 3 (444-447):
12345