Human Papillomavirus (HPV)-Related Carcinoma of the Oropharynx with Squamous Cell and Adenoid Cystic Carcinoma-Like Features: Report of a Case

被引:3
|
作者
Hodgson, Christina K. [1 ]
Bayon, Rodrigo [2 ]
Jensen, Chris S. [1 ]
Robinson, Robert A. [1 ]
Rajan, Anand K. D. [1 ]
机构
[1] Univ Iowa Hosp & Clin, Dept Pathol, 5239D 200 Hawkins Dr, Iowa City, IA 52242 USA
[2] Univ Iowa Hosp & Clin, Dept Otolaryngol, 200 Hawkins Dr, Iowa City, IA 52242 USA
来源
HEAD & NECK PATHOLOGY | 2021年 / 15卷 / 03期
关键词
HPV-related; Adenoid-cystic like features; HPV mRNA in situ hybridization; Multiphenotypic; Biphenotypic carcinoma; HMSC; HPV16; MULTIPHENOTYPIC SINONASAL CARCINOMA; LOW-GRADE ADENOCARCINOMA; MINOR SALIVARY-GLANDS; HPV-RELATED CARCINOMA; TONSIL; HEAD; TUMOR; BASE;
D O I
10.1007/s12105-020-01233-0
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
We describe the heretofore unreported case of an HPV-related carcinoma of the palatine tonsil with distinct areas of squamous cell- and adenoid cystic carcinoma-like differentiation in a 54-year old patient. The morphological, immunophenotypic and molecular findings of the tumor are illustrated. We discuss the parallels between the tumor and HPV-related multiphenotypic sinonasal carcinoma (HMSC) which is well-known to exhibit adenoid cystic carcinoma-like features. A review of the literature of high-risk HPV-associated non-squamous carcinomas of the oropharynx is presented.
引用
收藏
页码:1007 / 1016
页数:10
相关论文
共 50 条
  • [41] Analysis of Human Papillomavirus (HPV) and Polyomaviruses (HPyVs) in Adenoid Cystic Carcinoma (AdCC) of the Head and Neck Region Reveals Three HPV-Positive Cases with Adenoid Cystic-like Features
    Zupancic, Mark
    Holzhauser, Stefan
    Cheng, Liquin
    Ramqvist, Torbjorn
    Du, Juan
    Friesland, Signe
    Nasman, Anders
    Dalianis, Tina
    VIRUSES-BASEL, 2022, 14 (05):
  • [42] Basaloid squamous cell carcinoma of the esophagus with or without adenoid cystic features
    Li, TJ
    Zhang, YX
    Wen, J
    Cowan, DF
    Hart, J
    Xiao, SY
    ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2004, 128 (10) : 1124 - 1130
  • [43] ADENOID CYSTIC CARCINOMA OF THE BREAST - REPORT OF A CASE WITH UNUSUAL FEATURES
    MCLELLAN, PG
    TENNANT, R
    SAROKHAN, J
    SURGERY, 1953, 33 (06) : 905 - 908
  • [44] Human Papillomavirus-Related Small Cell Carcinoma of the Oropharynx
    Bishop, Justin A.
    Westra, William H.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2011, 35 (11) : 1679 - 1684
  • [45] Salivary Gland Like Breast Carcinoma/Adenoid Cystic Carcinoma: Case Report
    Acar, Turan
    Atahan, Murat Kemal
    Celik, Salih Can
    Yemez, Kursat
    Ulker, Gulden Balli
    Yigit, Seyran
    Tarcan, Ercument
    JOURNAL OF BREAST HEALTH, 2014, 10 (04): : 245 - 247
  • [46] Papillary Squamous Cell Carcinoma of the Cervix: Human Papillomavirus (HPV) Status and Clinicopathologic Features
    Schechter, S. A.
    Elshaikh, A.
    Walline, H.
    Skala, S. L.
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2020, 154 : S24 - S24
  • [47] Basaloid squamous cell carcinoma with adenoid cystic-like features of the head and neck region: A report of two cases
    Kusafuka, Kimihide
    Yagi, Haruna
    Baba, Satoshi
    Inagaki, Hiroshi
    Tsuchiya, Chinatsu
    Hirata, Kazuki
    Muramatsu, Aya
    Suzuki, Makoto
    Arai, Kazumori
    Terada, Tadashi
    PATHOLOGY INTERNATIONAL, 2020, 70 (10) : 767 - 774
  • [48] Adenoid cystic carcinoma of the Bartholin gland is not HPV-related: A case report and review of literature
    Nieuwenhuyzen-de Boer, Gatske M.
    Dasgupta, Shatavisha
    Ewing-Graham, Patricia C.
    Van Bockstal, Mieke R.
    PATHOLOGY RESEARCH AND PRACTICE, 2020, 216 (06)
  • [49] Basaloid carcinoma: Rare human papillomavirus-related variant of squamous cell carcinoma of the anorectum: A case report
    Gupta, Rajib Kumar
    Pillappa, Raghavendra
    Stone, Ilya
    Zafar, Nadeem
    INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2014, 57 (02) : 345 - U207
  • [50] Human papillomavirus-related carcinoma with adenoid cystic-like features: a series of five cases expanding the pathological spectrum
    Hang, Jen-Fan
    Hsieh, Min-Shu
    Li, Wing-Yin
    Chen, Jo-Yu
    Lin, Shih-Yao
    Liu, Shih-Hao
    Pan, Chin-Chen
    Kuo, Ying-Ju
    HISTOPATHOLOGY, 2017, 71 (06) : 887 - 896