Human Papillomavirus (HPV)-Related Carcinoma of the Oropharynx with Squamous Cell and Adenoid Cystic Carcinoma-Like Features: Report of a Case

被引：3
|
作者：
Hodgson, Christina K. [1 ]
Bayon, Rodrigo [2 ]
Jensen, Chris S. [1 ]
Robinson, Robert A. [1 ]
Rajan, Anand K. D. [1 ]
机构：
[1] Univ Iowa Hosp & Clin, Dept Pathol, 5239D 200 Hawkins Dr, Iowa City, IA 52242 USA
[2] Univ Iowa Hosp & Clin, Dept Otolaryngol, 200 Hawkins Dr, Iowa City, IA 52242 USA
来源：
HEAD & NECK PATHOLOGY | 2021年 / 15卷 / 03期
关键词：
HPV-related; Adenoid-cystic like features; HPV mRNA in situ hybridization; Multiphenotypic; Biphenotypic carcinoma; HMSC; HPV16; MULTIPHENOTYPIC SINONASAL CARCINOMA; LOW-GRADE ADENOCARCINOMA; MINOR SALIVARY-GLANDS; HPV-RELATED CARCINOMA; TONSIL; HEAD; TUMOR; BASE;
D O I：
10.1007/s12105-020-01233-0
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
We describe the heretofore unreported case of an HPV-related carcinoma of the palatine tonsil with distinct areas of squamous cell- and adenoid cystic carcinoma-like differentiation in a 54-year old patient. The morphological, immunophenotypic and molecular findings of the tumor are illustrated. We discuss the parallels between the tumor and HPV-related multiphenotypic sinonasal carcinoma (HMSC) which is well-known to exhibit adenoid cystic carcinoma-like features. A review of the literature of high-risk HPV-associated non-squamous carcinomas of the oropharynx is presented.
引用
收藏
页码：1007 / 1016
页数：10
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