High sensitivity detection of EGFR exon 20 T790M and C797S mutations using ICE COLD-FOR

被引：0
|
作者：
Wu, Grant
Jensen, Sheena
Scott, Karissa
Montagne, Erin
Stoddard, Jason
Krzycki, Phil
Schweikart, Courtney
Legendre, Benjamin L.
Eastlake, Philip
Richardson, Katherine A.
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-1390
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1390
引用
收藏
页数：4
相关论文
共 50 条
  • [41] Psorachromene induces apoptosis and suppresses tumor growth in NSCLC cells harboring EGFR L858R/T790M/C797S
    Wang, Tong-Hong
    Leu, Yann-Lii
    Chen, Chin-Chuan
    Li, Hsin-Jung
    Yang, Shuenn-Chen
    Huang, Kuo-Yen
    Chen, Chi-Yuan
    PHYTOTHERAPY RESEARCH, 2022, 36 (05) : 2116 - 2126
  • [42] Glioblastoma with novel EGFR mutations (T790M and exon 20 insertion) yet unresponsive to osimertinib: A case report
    Boongird, Atthaporn
    Lekcharoensombat, Nopphon
    Jinawath, Artit
    Theparee, Talent
    Jittapiromsak, Nutchawan
    Shuangshoti, Shanop
    Thorner, Paul Scott
    Teerapakpinyo, Chinachote
    GENES CHROMOSOMES & CANCER, 2023, 62 (07): : 423 - 429
  • [43] 阿法替尼治疗肺腺癌致EGFR T790M/C797S突变1例并文献复习
    郭曼
    曹玉风
    王苏
    青岛大学学报(医学版), 2024, 60 (01) : 144 - 147
  • [44] Very high sensitivity detection of K-RAS exon 2 mutations using fast COLD-FOR
    Candau, Reyes
    Shandilya, Harini
    Han, Ying
    Eastlake, Phil
    Kaldjian, Eric
    Makrigiorgos, G. Mike
    Gerard, Gary F.
    CANCER RESEARCH, 2010, 70
  • [45] Discovery of potent and selective next-generation EGFR inhibitors with activity against single, double, and triple mutant EGFR variants including T790M and C797S
    Huang, Wei-Sheng
    Nadworny, Sara
    Narasimhan, Narayana
    Eyermann, Charles J.
    Dalgarno, David C.
    Rivera, Victor M.
    Shakespeare, William C.
    CANCER RESEARCH, 2022, 82 (12)
  • [46] Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S
    Lategahn, Jonas
    Keul, Marina
    Kloevekorn, Philip
    Tumbrink, Hannah L.
    Niggenaber, Janina
    Mueller, Matthias P.
    Hodson, Luke
    Flasshoff, Maren
    Hardick, Julia
    Grabe, Tobias
    Engel, Julian
    Schultz-Fademrecht, Carsten
    Baumann, Matthias
    Ketzer, Julia
    Muehlenberg, Thomas
    Hiller, Wolf
    Guenther, Georgia
    Unger, Anke
    Mueller, Heiko
    Heimsoeth, Alena
    Golz, Christopher
    Blank-Landeshammer, Bernhard
    Kollipara, Laxmikanth
    Zahedi, Rene P.
    Strohmann, Carsten
    Hengstler, Jan G.
    van Otterlo, Willem A. L.
    Bauer, Sebastian
    Rauh, Daniel
    CHEMICAL SCIENCE, 2019, 10 (46) : 10789 - 10801
  • [47] Design and synthesis of 4th generation EGFR inhibitors against human triple (Del19/T790M/C797S) mutation
    Jeon, Jiyoung
    Jang, Sun Young
    Kwak, Eun Joo
    Lee, Sun Hoe
    Byun, Joo-Yun
    Kim, Yu -Yon
    Ahn, Young Gil
    Singh, Pargat
    Moon, Kyeongwon
    Kim, In Su
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 261
  • [48] Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor
    Nishiya, Naoyuki
    Oku, Yusuke
    Ishikawa, Chie
    Fukuda, Tsutomu
    Dan, Shingo
    Mashima, Tetsuo
    Ushijima, Masaru
    Furukawa, Yoko
    Sasaki, Yuka
    Otsu, Keishi
    Sakyo, Tomoko
    Abe, Masanori
    Yonezawa, Honami
    Ishibashi, Fumito
    Matsuura, Masaaki
    Tomida, Akihiro
    Seimiya, Hiroyuki
    Yamori, Takao
    Iwao, Masatomo
    Uehara, Yoshimasa
    CANCER SCIENCE, 2021, 112 (05) : 1963 - 1974
  • [49] Comparing outcomes of patients with epidermal growth factor receptor (EGFR) therapy resistant mutations (EXON 20 and T790M)
    Enver, M.
    Khalid, F.
    Khan, S.
    Ahmed, S.
    LUNG CANCER, 2019, 127 : S39 - S39
  • [50] Identification of Novel Fourth-Generation Allosteric Inhibitors Targeting Inactive State of EGFR T790M/L858R/C797S and T790M/L858R Mutations: A Combined Machine Learning and Molecular Dynamics Approach
    Bhanja, Kousik K.
    Patra, Niladri
    JOURNAL OF PHYSICAL CHEMISTRY B, 2025,
12345