Phytochemical screening and antimicrobial activity of Coccinia cordifolia L. plant

被引:0
|
作者
Khatun, Shahanaz [2 ]
Pervin, Farzana [2 ]
Karim, Mohammad Rezaul [3 ]
Ashraduzzaman, Mohammad [4 ]
Rosma, Ahmad [1 ]
机构
[1] Univ Sains Malaysia, Sch Ind Technol, Bioproc Technol Div, George Town, Malaysia
[2] Rajshahi Univ, Dept Biochem & Mol Biol, Rajshahi 6205, Bangladesh
[3] Univ Malaysia Pahang, Fac Ind Sci & Technol, Kuantan, Pahang, Malaysia
[4] Rajshahi Univ Engn & Technol, Dept Chem, Rajshahi, Bangladesh
关键词
Medicinal plants; Antimicrobial activity; Coccinia cordifolia; phytochemical; ANTIBACTERIAL ACTIVITY; GRANDIS;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The medicinal plant, Coccinia cordifolia L. was analyzed for its chemical composition. The antimicrobial activities of the methanol, water, ethanol and ethyl acetate extracts of Coccinia cordifolia L. plant were evaluated against some Gram positive bacteria (Sarcina lutea, Bacillus subtilis and Staphylococcus aureus), Gram negative bacteria (Salmonella typhi, Shigella dysenteriae and Escherichia coli) and fungi (Candida albicans, Aspergillus niger and Penicillium notatum). Chemical analysis showed that the plant is rich in nutrients, especially antioxidant compounds such as total phenol, vitamin C and beta-carotene. Phytochemical screening showed that the methanolic extract contains the bioactive constituents such as tannins, saponins, phenols, flavonoids and terpenoids. In the methanolic extract of the plant, promising antimicrobial potential was observed against the tested microorganism. Methanolic extract showed highest activity against Shigella dysenteriae, Escherichia coli, Staphylococcus aureus, and Candida albicans compared to the other extracts. Water extract showed less antimicrobial activity as compared to other extractants.
引用
收藏
页码:757 / 761
页数:5
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