Lessons Learned from Clinical Trials in Acute Heart Failure: Phase 3 Drug Trials

被引：3

作者：

O'Connor, Christopher M. ^{[1
]}

Fiuzat, Mona ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Div Cardiol, Durham, NC 27710 USA

来源：

HEART FAILURE CLINICS | 2011年 / 7卷 / 04期

关键词：

Acute heart failure; Phase 3 clinical trials; Endpoints; Efficacy; Safety; RANDOMIZED CONTROLLED-TRIAL; ANTAGONIST; ROLOFYLLINE; NESIRITIDE;

D O I：

10.1016/j.hfc.2011.06.013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Phase 3 clinical trials in acute heart failure are conducted to allow safety and efficacy data to be collected for the evaluation of treatment strategies, including drugs, devices, diagnostics, or nonpharmacological interventions. There are several important features regarding the conduct of phase 3 clinical trials in acute heart failure. This article describes in detail these important aspects of conducting phase 3 clinical trials in an acute heart failure population.

引用

页码：451 / +

页数：7

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