Recent progress in the Morita-Baylis-Hillman reactions

被引：61
|
作者：
Iwabuchi, Y [1 ]
Hatakeyama, S [1 ]
机构：
[1] Nagasaki Univ, Fac Pharmaceut Sci, Nagasaki 8526521, Japan
来源：
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 2002年 / 60卷 / 01期
关键词：
Morita-Baylis-Hillman reaction; nucleophilic catalysis; rate enhancement; asymmetric synthesis; asymmetric catalysis; diastereoselective reaction; amine catalyst; phosphine catalyst; calcogeno-Baylis-Hillman reactions; tandem Michael-aldol reaction; enzymatic resolution; kinetic resolution;
D O I：
10.5059/yukigoseikyokaishi.60.2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Morita-Baylis-Hillman reaction, alpha-hydroxyalkylation of activated olefins, has attracted considerable research interest because of the synthetic utility of the densely functionalized product as well as the exquisite tandem Michael-aldol reaction process under nucleophilic catalysis. This review gives an overview on recent remarkable progress in the Morita-Baylis-Hillman reactions. Several other successful methods affording the Morita-Baylis-Hillman type adducts are also reviewed by focusing their imaginative strategies.
引用
收藏
页码：2 / 14
页数：13
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