The radiosensitive effect of apatinib for hepatocellular carcinoma patient with big paraspinal metastasis A case report

被引：8
|
作者：
Zhu, Hong [1 ]
Zhao, Yaqin [1 ]
Wang, Xin [1 ]
机构：
[1] Sichuan Univ, West China Hosp, Dept Med Oncol, Chengdu 610041, Sichuan, Peoples R China
来源：
MEDICINE | 2018年 / 97卷 / 02期
关键词：
apatinib; hepatocellular carcinoma (HCC); radiosensitizer; radiotherapy; CHEMOTHERAPY;
D O I：
10.1097/MD.0000000000009598
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Rationale: Hepatocellular carcinoma (HCC) is a highly invasive cancer associated with great mortality rates. The prognosis of advanced HCC is very poor. Patient concerns: Here, we report a HCC patient with a big paraspinal metastasis with 10cm in diameter who failed the treatment of sorafenib. Diagnoses: Sorafenib refractory HCC with big paraspinal metastasis. Interventions: The concurrent treatment of apatinib with stereotactic body radiotherapy (SBRT). Outcomes: The paraspinal metastasis with 10cm in diameter showed nearly complete response. Lessons: We think that the apatinib may be a good choice for HCC and it may function as a radiosensitizer of HCC. However, it warrants further investigation in the future prospective clinical studies.
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页数：4
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