The JAK1/2 inhibitor ruxolitinib in COVID-19 with severe systemic hyperinflammation

被引:0
|
作者
La Rosee, F. [1 ,2 ]
Bremer, H. -C. [3 ]
Hochhaus, A. [4 ]
Birndt, S. [4 ]
Fellhauer, M. [5 ]
Henkes, M. [6 ]
Russo, S. G. [7 ,8 ,9 ]
La Rosee, P. [1 ,6 ]
机构
[1] Friedrich Schiller Univ Jena, Univ Klinikum Jena, Fak Med, Jena, Germany
[2] Tech Univ Dresden, Med Fak Carl Gustav Carus, Dresden, Germany
[3] Schwarzwald Baar Klinikum, Lungenzentrum Donaueschingen, Villingen Schwenningen, Germany
[4] Univ Klinikum Jena, Klin Innere Med 2, Jena, Germany
[5] Schwarzwald Baar Klinikum, Apotheke Inst Klin Pharm, Villingen Schwenningen, Germany
[6] Schwarzwald Baar Klinikum, Klin Innere Med Hamatol Onkol Immunol Infekt & Pa, Villingen Schwenningen, Germany
[7] Schwarzwald Baar Klinikum, Klin Anasthesiol Intens Notfall & Schmerzmed, Villingen Schwenningen, Germany
[8] Univ Witten Herdecke, Fak Gesundheit, Witten, Germany
[9] Univ Gottingen, Fak Med, Gottingen, Germany
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
582
引用
收藏
页码:198 / 198
页数:1
相关论文
共 50 条
  • [31] Ruxolitinib: a new JAK1/2 inhibitor that offers promising options for treatment of myelofibrosis
    Ostojic, Alen
    Vrhovac, Radovan
    Verstovsek, Srdan
    FUTURE ONCOLOGY, 2011, 7 (09) : 1035 - 1043
  • [32] Comparison of the crystal structures of the JAK1/2 inhibitor ruxolitinib and its hydrate and phosphate
    Peng, Ziyu
    Ye, Long
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2024, 80 : 440 - +
  • [33] Efficacy of JAK1/2 inhibitor ruxolitinib in severe GVHD with capillary leak syndrome in a 12 years old boy
    Fremond, M. -L.
    Chomton, M.
    Cros, G.
    Touzot, F.
    Helley, D.
    Hulin, A.
    Moshous, D.
    Neven, B.
    Blanche, S.
    BONE MARROW TRANSPLANTATION, 2015, 50 : S457 - S458
  • [34] Differential NK-suppressive capacity of the JAK2 inhibitor Pacritinib when compared to the JAK1/2 inhibitor Ruxolitinib
    Wolf, D.
    Rudolph, J.
    Brossart, P.
    Schoenberg, K.
    ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 26 - 26
  • [35] Allogeneic hematopoietic cell transplantation for myelofibrosis in patients pretreated with the JAK1 and JAK2 inhibitor ruxolitinib
    Jaekel, N.
    Behre, G.
    Behning, A.
    Wickenhauser, C.
    Lange, T.
    Niederwieser, D.
    Al-Ali, H. K.
    BONE MARROW TRANSPLANTATION, 2014, 49 (02) : 179 - 184
  • [36] The Impact of Jak1/Jak2 Inhibitor Ruxolitinib on the Spleen Size and Symptom Burden in Myeloproliferative Diseases
    Aktimur, Sude H.
    Malkan, Umit Y.
    Eyupoglu, Damla N.
    Haznedaroglu, Ibrahim C.
    Kelkitli, Engin
    Atay, Hilmi M.
    Gunes, Gursel
    Etgul, Sezgin
    Aslan, Tuncay
    Goker, Hakan
    Sayinalp, Nilgun
    Aksu, Salih
    Ozcebe, Osman I.
    Buyukasik, Yahya
    Turgut, Mehmet
    UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, 2016, 26 (03): : 153 - 158
  • [37] Allogeneic hematopoietic cell transplantation for myelofibrosis in patients pretreated with the JAK1 and JAK2 inhibitor ruxolitinib
    N Jaekel
    G Behre
    A Behning
    C Wickenhauser
    T Lange
    D Niederwieser
    H K Al-Ali
    Bone Marrow Transplantation, 2014, 49 : 179 - 184
  • [38] IMPLICATIONS OF RUXOLITINIB, JAK1/JAK2 INHIBITOR, ON THE GRAFT EFFECT AGAINST LEUKEMIA IN NK CELLS
    Carmen, Mestre-Duran
    Carla, Martin-Cortazar
    Al-Fonso, Navarro-Zapata
    David, Bueno
    Laura, Clares-Villa
    Alicia, Pernas
    Karima, Al-akioui
    Luisa, Sisinni
    Blanca, Garcia-Solis
    Victor, Galan
    Nerea, Matamala
    Adela, Escudero
    Cristina, Ferreras
    Antonio, Perez-Martinez
    HAEMATOLOGICA, 2021, 106 (10) : 29 - 30
  • [39] Resolution of bone marrow fibrosis in a patient receiving JAK1/JAK2 inhibitor treatment with ruxolitinib
    Wilkins, Bridget S.
    Radia, Deepti
    Woodley, Claire
    El Farhi, Sarah
    Keohane, Clodagh
    HAEMATOLOGICA, 2013, 98 (12) : 1872 - 1876
  • [40] The Prognostic Impact of the Mutational Profile in Patients with Myelofibrosis in the Era of the JAK1/JAK2-Inhibitor Ruxolitinib
    Al-Ali, Haifa Kathrin
    Wang, Song-Yau
    Jaekel, Nadja
    Koehler, Anne
    Krahl, Rainer
    Hubert, Karolin
    Lange, Thoralf
    Roskos, Martin
    Stengel, Rayak
    Kovacs, Ines
    Scarlett, Schwabe
    Schubert, Karoline
    Wildenberger, Kathrin
    Schneider, Melanie
    Koehler, Elisabeth
    Niederwieser, Dietger
    BLOOD, 2014, 124 (21)