In this paper, we examine self-affine time series and their persistence. Time series are defined to be self-affine if their power-spectral density scales as a power of their frequency. Persistence can be classified in terms of range, short or long range, and in terms of strength, weak or strong. Self-affine time series are scale-invariant, thus they always exhibit long-range persistence. Synthetic self-affine time series are generated using the Fourier power-spectral method. We generate fractional Gaussian noises (fGns), -1 less than or equal to beta less than or equal to 1, where beta is the power-spectral exponent. These are summed to give fractional Brownian motions (fBms), 1 less than or equal to beta less than or equal to 3, where the series are self-affine fractals with fractal dimension 1 less than or equal to D less than or equal to 2; beta = 2 is a Brownian motion. With beta > 1, the time series are non-stationary and moments of the time series depend upon its length; with beta < 1 the time series are stationary. We define self-affine time series with beta > 1 to have strong persistence and with beta < 1 to have weak persistence. We use a variety of techniques to quantify the strength of persistence of synthetic self-affine time series with -3 less than or equal to beta less than or equal to 5. These techniques are effective in the following ranges: (1) semivariograms, 1 less than or equal to beta less than or equal to 3, (2) rescaled-range (R/S) analyses, -1 less than or equal to beta less than or equal to 1, (3) Fourier spectral techniques, all values of beta, and (4) wavelet variance analyses, all values of beta. wavelet variance analyses lack many of the inherent problems that are found in Fourier power-spectral analysis. (C) 1999 Published by Elsevier Science B.V. All rights reserved.